ASAH1 and TSC22D1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ASAH1	TSC22D1
Description		N-acylsphingosine amidohydrolase 1	TSC22 domain family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Lysosome Early Endosome Endoplasmic Reticulum Lysosomal Lumen Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Nucleus Cytoplasm
	Molecular Function	Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides N-acylsphingosine Amidohydrolase Activity Fatty Acid Amide Hydrolase Activity Ceramidase Activity	Protein Binding
	Biological Process	Fatty Acid Metabolic Process Keratinocyte Differentiation Sphingosine Biosynthetic Process Ceramide Biosynthetic Process Ceramide Catabolic Process Regulation Of Steroid Biosynthetic Process Regulation Of Programmed Necrotic Cell Death Cellular Response To Tumor Necrosis Factor	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II
Pathways		Glycosphingolipid metabolism Neutrophil degranulation
Drugs
Diseases
GWAS		Atrial fibrillation ( 28416818 30061737 29892015) Night sleep phenotypes ( 27126917) Obesity ( 21552555) Type 2 diabetes ( 32499647)	Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Body mass index ( 25760438) Refractive error ( 32231278) Rosacea symptom severity ( 29771307)
Interacting Genes		6 interacting genes: CAMK1D HSPB2 SETDB1 SMPD1 SRPK1 TSC22D1	56 interacting genes: A2M APLP1 ASAH1 CACNA1A CARHSP1 CCDC88C CCDC90B CHD3 CKAP2 CORO2B CRMP1 DDAH2 DNASE1 DNMT3B EED ERG28 FAF1 FAM20C FBN3 GNB2 GNB5 GORASP2 GTF2F2 HMGXB4 KMT2B KMT2C LPAR6 LRIF1 MAP3K12 MCM3AP NCOA5 NTAQ1 OTUB1 PDHB PRKCI PTN QARS1 RFXAP RGS1 RPL5 SETDB1 SP110 SPACA9 SPRED1 TAF5L TGFBR1 TLE1 TP53 TSC22D4 UBE2D1 UNC119 VIM WDR73 WIZ WNK1 ZC3HC1
Entrez ID		427	8848
HPRD ID		01969	07414
Ensembl ID		ENSG00000104763	ENSG00000102804
Uniprot IDs		A8K0B6 Q13510 Q53H01	A0A024RDV8 A0A087X0H8 A8K3Y6 Q15714
PDB IDs		5U7Z 6MHM
Enriched GO Terms of Interacting Partners?
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