MEOX1 and PRKAG1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MEOX1	PRKAG1
Description		mesenchyme homeobox 1	protein kinase AMP-activated non-catalytic subunit gamma 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nucleotide-activated Protein Kinase Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding HMG Box Domain Binding Sequence-specific Double-stranded DNA Binding	Protein Kinase Activity CAMP-dependent Protein Kinase Activity Protein Binding ATP Binding CAMP-dependent Protein Kinase Regulator Activity AMP Binding Protein Kinase Regulator Activity Protein Kinase Binding ADP Binding
	Biological Process	Somite Specification Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Biological_process Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Differentiation Somite Development Sclerotome Development	Regulation Of Glycolytic Process Protein Phosphorylation Fatty Acid Biosynthetic Process Signal Transduction Spermatogenesis Positive Regulation Of Gene Expression Cellular Response To Glucose Starvation Positive Regulation Of Protein Kinase Activity Regulation Of Catalytic Activity Import Into Nucleus Regulation Of Protein Serine/threonine Kinase Activity
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Macroautophagy Activation of PPARGC1A (PGC-1alpha) by phosphorylation Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of TP53 Activity through Phosphorylation Lipophagy Activation of AMPK downstream of NMDARs
Drugs			Adenosine phosphate Acetylsalicylic acid Fostamatinib
Diseases
GWAS		Fractures ( 30158200)	Adult body size ( 32376654) Bipolar disorder ( 31043756) Body mass index ( 29273807) HDL cholesterol ( 30275531) Pulse pressure ( 27618447) Red cell distribution width ( 32888494) Systolic blood pressure ( 27618447 30578418)
Interacting Genes		99 interacting genes: ACBD4 ACOT12 ALOX5 ANAPC2 APP APPL1 ATG9A BANP BNIP2 BYSL C14orf119 C1orf109 C1orf50 C2CD6 CACNB3 CCDC102B CCDC103 CDC34 CIAO1 CIB3 CKS1B CNOT11 CSNK2A1 CWF19L2 CYFIP1 DCX DUSP3 EIF4A3 EIF4EBP1 EMD FAM126B FMR1 GCC1 GEMIN2 GPANK1 GYS1 HMBOX1 HMGB3 HOMER3 HOXC8 INPP5J KANK2 KCTD7 L3MBTL2 LMNA MAPK9 MBD3 MCRS1 MEF2A MID1 MID2 MKRN3 MLX MORF4L1 MVP NAGK NDOR1 NEIL2 OSGIN1 PAGE3 PARVG PAX1 PAX3 PCP2 PDE4C PELI2 PIN1 PLCD4 PM20D2 POLR3GL PPM1F PRKAG1 PRKN QRICH1 RAD52 RANBP3 RBM41 RBM5 SDCBP SEC14L4 SOX10 SPAG8 SPIC SYT17 TCEANC TCP11L1 TEX33 TRAPPC2L TRIM41 TRIML2 TRIP10 TXLNA TXNL4B UBE2R2 UBXN2B UBXN7 UNC45A ZCCHC10 ZNF410	31 interacting genes: ACACA AP1S3 C1orf94 CBS CRBN EIF3G KCNN4 KEAP1 KRTAP1-1 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP4-12 KRTAP4-2 KRTAP9-2 KRTAP9-8 MEOX1 MEOX2 PAICS PAX6 PLEKHF2 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG2 SHMT2 TEKT1 TNFAIP1 TUBA1C
Entrez ID		4222	5571
HPRD ID		02537	04118
Ensembl ID		ENSG00000005102	ENSG00000181929
Uniprot IDs		P50221	A0A024R125 P54619
PDB IDs			2UV4 2UV5 2UV6 2UV7 4CFE 4CFF 4RER 4REW 4ZHX 5EZV 5ISO 6B1U 6B2E 6C9F 6C9G 6C9H 6C9J
Enriched GO Terms of Interacting Partners?
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