RAB8A and KCNN1

		RAB8A	KCNN1
Description		RAB8A, member RAS oncogene family	potassium calcium-activated channel subfamily N member 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endosome Centrosome Centriole Cytosol Plasma Membrane Cilium Synaptic Vesicle Postsynaptic Density Trans-Golgi Network Transport Vesicle Midbody Phagocytic Vesicle Membrane Trans-Golgi Network Membrane Neuronal Cell Body Dendritic Spine Phagocytic Vesicle Recycling Endosome Membrane Extracellular Exosome Non-motile Cilium Glutamatergic Synapse	Plasma Membrane Voltage-gated Potassium Channel Complex Neuron Projection Neuronal Cell Body Synapse
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Kinase Binding Small GTPase Binding Myosin V Binding	Inward Rectifier Potassium Channel Activity Calmodulin Binding Calcium-activated Potassium Channel Activity Small Conductance Calcium-activated Potassium Channel Activity
	Biological Process	Vesicle Docking Involved In Exocytosis Autophagy Axonogenesis Protein Secretion Regulation Of Autophagy Regulation Of Exocytosis Cellular Response To Insulin Stimulus Regulation Of Long-term Neuronal Synaptic Plasticity Golgi Vesicle Fusion To Target Membrane Regulation Of Protein Transport Cilium Assembly Protein Localization To Plasma Membrane Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Vesicle-mediated Transport In Synapse	Ion Transport Potassium Ion Transport Chemical Synaptic Transmission Potassium Ion Transmembrane Transport
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium TBC/RABGAPs RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Ca2+ activated K+ channels
Drugs			Procaine Miconazole Trimebutine
Diseases
GWAS		Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 27863252) Mean platelet volume ( 32888494 27863252) Platelet count ( 32888494) Red cell distribution width ( 32888494)	Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Mean reticulocyte volume ( 32888494)
Interacting Genes		34 interacting genes: ASNS BAG6 BIRC6 GDI2 IKBKG JAK3 KCNN1 MALT1 MAP4K2 MDM2 MYO5C MYO9B NR2F6 OCRL ODF2 OPTN PDE6D PQBP1 PRKACA RAB11A RAB13 RAB3IL1 RAB3IP RABIF RIMS2 RPH3A RPH3AL STEAP1 SYTL1 SYTL4 TAS2R9 TFRC TPM4 UGT2B15	5 interacting genes: CALM1 CALM2 CALM3 FXR1 RAB8A
Entrez ID		4218	3780
HPRD ID		01296	04282
Ensembl ID		ENSG00000167461	ENSG00000105642
Uniprot IDs		A0A024R7I3 P61006	Q92952
PDB IDs		3QBT 3TNF 4LHV 4LHW 4LHX 4LHY 4LHZ 4LI0 5SZI 6RIR 6SQ2 6STF 6STG 6ZSI 6ZSJ 7BWT
Enriched GO Terms of Interacting Partners?
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