MAT2A and PRC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MAT2A	PRC1
Description		methionine adenosyltransferase 2A	protein regulator of cytokinesis 1
Image
GO Annotations	Cellular Component	Cytosol Methionine Adenosyltransferase Complex	Spindle Pole Nucleus Nucleoplasm Chromosome Cytoplasm Spindle Cytosol Spindle Microtubule Plasma Membrane Microtubule Cytoskeleton Midbody Intercellular Bridge Contractile Ring Mitotic Spindle Midzone
	Molecular Function	Methionine Adenosyltransferase Activity Protein Binding ATP Binding Identical Protein Binding Metal Ion Binding	Protein Binding Microtubule Binding Kinesin Binding Protein Kinase Binding
	Biological Process	S-adenosylmethionine Biosynthetic Process One-carbon Metabolic Process Protein Hexamerization Protein Heterooligomerization Cellular Response To Leukemia Inhibitory Factor	Mitotic Spindle Elongation Microtubule Cytoskeleton Organization Microtubule Bundle Formation Positive Regulation Of Cell Population Proliferation Regulation Of Cytokinesis Mitotic Spindle Midzone Assembly Cell Division
Pathways		Methylation	RHO GTPases activate CIT
Drugs		Ademetionine
Diseases
GWAS		Coronary artery disease ( 29212778 30104761) Dysmenorrheic pain ( 27454463) Myocardial infarction ( 33532862) Urinary albumin excretion ( 30220432)	Breast cancer ( 29059683 25038754) Mean platelet volume ( 32888494 27863252) Multisite chronic pain ( 33830993 31194737) Red cell distribution width ( 32888494) Type 2 diabetes ( 22885922 24509480 30054458 30297969 26818947 32499647 20581827 30718926 28869590)
Interacting Genes		8 interacting genes: CUL3 HGS MAT1A MAT2B OGT PRC1 TMEM213 UBE2I	30 interacting genes: AKAP9 CASK CCDC85B CCNA2 CCNB1 CCNE1 CDK1 CDK2 CINP FXR2 KIF3B KIF4A KLC2 KLC4 KRT20 MAT2A NDEL1 OGT PCM1 PKIA PLK1 RACGAP1 RBM10 RPA2 SF3B2 SLAIN1 SUMO2 TRIM37 USHBP1 YWHAE
Entrez ID		4144	9055
HPRD ID		03275	17899
Ensembl ID		ENSG00000168906	ENSG00000198901
Uniprot IDs		A0A140VJP5 P31153	A0A024RC67 O43663
PDB IDs		2P02 4KTT 4KTV 4NDN 5A19 5A1G 5A1I 5UGH 6FAJ 6FBN 6FBO 6FBP 6FCB 6FCD 6FWB 6G6R 6P9V	3NRX 3NRY 4L3I 4L6Y 5KMG
Enriched GO Terms of Interacting Partners?
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