MAFG and PIDD1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		MAFG	PIDD1
Description		MAF bZIP transcription factor G	p53-induced death domain protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Protein Heterodimerization Activity Sequence-specific Double-stranded DNA Binding	Endopeptidase Activity Death Receptor Binding Protein Binding
	Biological Process	In Utero Embryonic Development Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Adult Behavior Regulation Of Cellular PH Regulation Of Cell Population Proliferation Regulation Of Epidermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To DNA Damage Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Protein Autoprocessing Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways		Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production	TP53 Regulates Transcription of Caspase Activators and Caspases
Drugs
Diseases
GWAS			Breast cancer ( 29059683)
Interacting Genes		26 interacting genes: ATF3 BACH2 BATF3 CHD3 CREBBP CYP2E1 DDIT3 GTF2A1L HIF1A HOMEZ HOXD12 MAF MAFF MAPK3 MED31 NFE2 NFE2L1 NFE2L2 NFIL3 PAX6 PIDD1 PPP1CA PRRX1 RBM48 SNRPN VIM	15 interacting genes: AFP CASP2 CCDC85B CRADD EFEMP2 FADD HSD17B14 KHDC4 MADD MAFG MDFI MTNR1B POGZ SOX8 TEAD3
Entrez ID		4097	55367
HPRD ID		03605	11284
Ensembl ID		ENSG00000197063	ENSG00000177595
Uniprot IDs		A0A024R8X1 O15525	Q9HB75
PDB IDs			2OF5
Enriched GO Terms of Interacting Partners?
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