MIR200C and CPSF1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		MIR200C	CPSF1
Description		microRNA 200c	cleavage and polyadenylation specific factor 1
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	Protein Binding Enzyme Binding MRNA 3'-UTR AU-rich Region Binding
	Biological Process	Negative Regulation Of Cytokine Production Positive Regulation Of Neuron Projection Development Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Positive Regulation Of Endothelial Cell Differentiation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Protein Kinase B Signaling Regulation Of Cardiac Muscle Contraction Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Interleukin-33 Production Negative Regulation Of Neuron Death Negative Regulation Of Voltage-gated Calcium Channel Activity Response To Amyloid-beta Regulation Of Vascular Endothelial Cell Proliferation Positive Regulation Of Mesodermal Cell Differentiation Negative Regulation Of Calcium Ion Import Across Plasma Membrane	MRNA Polyadenylation Pre-mRNA Cleavage Required For Polyadenylation
Pathways			Transport of Mature mRNA Derived from an Intronless Transcript tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS			Educational attainment ( 25201988)
Interacting Genes		89 interacting genes: AIMP2 AQR ATXN2L C1QBP CHERP CPSF1 CRTAP DARS1 DDX1 DDX21 DDX23 DDX3X DHX36 DHX37 EDC4 EIF2AK2 ELAC1 EPRS1 ESRP1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LIN28A LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT16L1 NUFIP2 PDCD11 PTBP1 PTBP3 PTCD3 PUF60 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCB SART3 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B TRIM56 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	57 interacting genes: CSTF2T GLIS2 HMOX1 IL7R INCA1 MCM2 MIR1-2 MIR106B MIR107 MIR122 MIR128-2 MIR138-1 MIR138-2 MIR143 MIR155 MIR15A MIR15B MIR16-2 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200C MIR205 MIR206 MIR20B MIR21 MIR214 MIR221 MIR29A MIR31 MIR34A MIR34B MIR7-1 MIR92A1 MIR92A2 MIR98 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I NEDD4 PAPOLA POLR2A PRRC2A REL TAF11 TAF12 TAF13 TAF5 TAF7
Entrez ID		406985	29894
HPRD ID			05823
Ensembl ID		ENSG00000207713	ENSG00000071894
Uniprot IDs			Q10570
PDB IDs			6BLY 6BM0 6DNH 6F9N 6FBS 6FUW 6URG 6URO
Enriched GO Terms of Interacting Partners?
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