MIR16-1 and MSI2

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		MIR16-1	MSI2
Description		microRNA 16-1	musashi RNA binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Extracellular Exosome Extracellular Vesicle	Cytoplasm Cytosol Polysome Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Complex Binding MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding Protein Binding Poly(U) RNA Binding Identical Protein Binding
	Biological Process	Branching Involved In Blood Vessel Morphogenesis Negative Regulation Of Endothelial Cell Proliferation Negative Regulation Of Cell Population Proliferation Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Angiogenesis Negative Regulation Of NF-kappaB Transcription Factor Activity Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Translation Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Inflammatory Response Cellular Response To Glucose Stimulus Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Placenta Blood Vessel Development Negative Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Negative Regulation Of Trophoblast Cell Migration Negative Regulation Of Mesenchymal Stem Cell Proliferation Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Cell Chemotaxis To Fibroblast Growth Factor Negative Regulation Of Endothelial Cell Chemotaxis To Vascular Endothelial Growth Factor Positive Regulation Of Connective Tissue Replacement Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Stem Cell Development
Pathways			RHOBTB2 GTPase cycle
Drugs
Diseases
GWAS			Birth weight ( 31043758) Chronotype ( 30696823) Coronary artery calcification ( 23870195) Decreased low contrast letter acuity in multiple sclerosis ( 31289819) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Freckles ( 29895819) Height ( 31562340) Male-pattern baldness ( 29146897 27182965) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494 27863252) Metabolite levels ( 23823483) Monocyte count ( 32888494) Neutrophil count ( 32888494) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Platelet count ( 32888494) Plateletcrit ( 32888494 27863252) Pulse pressure ( 30224653) Rapid automised naming of pictures ( 30741946) Refractive error ( 32231278) Schizophrenia ( 28991256 30285260) White blood cell count ( 32888494)
Interacting Genes		71 interacting genes: APOBEC3B C1QBP CPSF7 CRTAP DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 FAM98A FAM98B FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KNOP1 LARP7 LIN28A LRPPRC MATR3 MSI2 NONO NUDT21 PDCD11 PGAM5 PRMT1 PTBP1 PTBP3 PUF60 RARS1 RBFOX2 RBM14 RBM47 RTCA RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SUGP2 SYNCRIP TAF15 TRA2A TRA2B UPF1 USP36 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	67 interacting genes: DYNLL2 GRB2 HNRNPH1 HNRNPH2 MEOX2 MIR1-1 MIR106A MIR106B MIR10B MIR128-1 MIR128-2 MIR138-2 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29B1 MIR29B2 MIR29C MIR34A MIR34B MIR34C MIR363 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I
Entrez ID		406950	124540
HPRD ID			07438
Ensembl ID		ENSG00000208006	ENSG00000153944
Uniprot IDs			B4DHE8 Q96DH6
PDB IDs			6C8U 6DBP 6NTY
Enriched GO Terms of Interacting Partners?
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