MIR1-1 and ZNF385A

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		MIR1-1	ZNF385A
Description		microRNA 1-1	zinc finger protein 385A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm Dendrite Neuronal Cell Body
	Molecular Function	RNA Polymerase II Complex Binding MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	P53 Binding DNA Binding RNA Binding MRNA 3'-UTR Binding Zinc Ion Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cell Fate Commitment Positive Regulation Of Heart Rate Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Myotube Differentiation Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Transporter Activity Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Endothelial Cell Differentiation Negative Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Sarcomere Organization Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Ventricular Septum Morphogenesis Positive Regulation Of Cardiac Muscle Contraction Cell Migration Involved In Coronary Vasculogenesis Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity By Adrenergic Receptor Signaling Pathway Involved In Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of Canonical Wnt Signaling Pathway Reversible Differentiation Negative Regulation Of Delayed Rectifier Potassium Channel Activity Positive Regulation Of Sprouting Angiogenesis Positive Regulation Of Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization Negative Regulation Of Cardiac Conduction Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Negative Regulation Of Membrane Repolarization During Cardiac Muscle Cell Action Potential Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane Positive Regulation Of Mesoderm Formation Negative Regulation Of Calcium Ion Export Across Plasma Membrane Positive Regulation Of Cardiac Vascular Smooth Muscle Cell Differentiation Positive Regulation Of Cardiac Muscle Cell Differentiation Negative Regulation Of Myoblast Proliferation Positive Regulation Of Skeletal Muscle Cell Differentiation	Apoptotic Process Cellular Response To DNA Damage Stimulus MRNA Localization Resulting In Posttranscriptional Regulation Of Gene Expression Megakaryocyte Development Positive Regulation Of Fat Cell Differentiation Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Cytoplasmic Translation
Pathways			TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest Regulation of TP53 Activity through Association with Co-factors Transcriptional activation of cell cycle inhibitor p21
Drugs
Diseases
GWAS		Prostate cancer ( 23535732) Subjective response to lithium treatment in bipolar disorder ( 26503763)	Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		89 interacting genes: ADARB1 APOBEC3B AQR ATXN2L C1QBP CPSF7 CRTAP DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KIN KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 NUFIP2 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SART3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP1 SUGP2 SYNCRIP TAF15 TRA2A TRA2B TRIM25 TRIM71 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346 ZNF385A	10 interacting genes: MIR1-1 MIR155 MIR19A MIR19B1 MIR19B2 MIR34C MIR9-1 MIR9-2 MIR9-3 OGT
Entrez ID		406904	25946
HPRD ID			16448
Ensembl ID		ENSG00000199017	ENSG00000161642
Uniprot IDs			A0A024RB56 Q96PM9
PDB IDs
Enriched GO Terms of Interacting Partners?
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