MIRLET7A1 and APOBEC3B

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		MIRLET7A1	APOBEC3B
Description		microRNA let-7a-1	apolipoprotein B mRNA editing enzyme catalytic subunit 3B
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Extracellular Exosome Extracellular Vesicle	P-body Nucleus Nucleoplasm Cytoplasm
	Molecular Function	MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Deoxycytidine Deaminase Activity
	Biological Process	Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Interleukin-6-mediated Signaling Pathway Deadenylation Involved In Gene Silencing By MiRNA	Cytidine Deamination Negative Regulation Of Transposition Cytidine To Uridine Editing Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Defense Response To Virus DNA Cytosine Deamination DNA Demethylation
Pathways			mRNA Editing: C to U Conversion Formation of the Editosome
Drugs
Diseases
GWAS			Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Breast cancer ( 29059683) Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
Interacting Genes		101 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CPSF2 CPSF6 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FAM98B FUS G3BP2 GRSF1 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC LSM10 LSM11 MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PUM1 PUM2 PURA QARS1 RARS1 RBFOX2 RBM10 RBM14 RBM4 RTCB SAFB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B TRIM25 TUT4 TUT7 U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	61 interacting genes: AGR2 BNIP2 MIR1-1 MIR1-2 MIR106A MIR10B MIR128-1 MIR128-2 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A2 MIR19A MIR19B1 MIR200A MIR200B MIR205 MIR20A MIR20B MIR21 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR9-1 MIR9-2 MIR9-3 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MSL2
Entrez ID		406881	9582
HPRD ID			06169
Ensembl ID		ENSG00000199165	ENSG00000179750
Uniprot IDs			Q9UH17
PDB IDs			2NBQ 5CQD 5CQH 5CQI 5CQK 5SXG 5SXH 5TD5 5TKM 6NFK 6NFL 6NFM
Enriched GO Terms of Interacting Partners?
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