VWC2L and CXCL5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		VWC2L	CXCL5
Description		von Willebrand factor C domain containing 2 like	C-X-C motif chemokine ligand 5
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space AMPA Glutamate Receptor Complex Synapse	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding	Protein Binding Chemokine Activity Identical Protein Binding CXCR Chemokine Receptor Binding
	Biological Process	Negative Regulation Of BMP Signaling Pathway Positive Regulation Of Neuron Differentiation	Chemotaxis Inflammatory Response Signal Transduction Cell-cell Signaling Positive Regulation Of Cell Population Proliferation Neutrophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Degraded stimulus continuous performance test score ( 31596458) Dietary fat liking ( 32516399) Household income (MTAG) ( 31844048) Neuroticism ( 29255261) PR interval ( 23534349)	CXCL5 levels ( 25147954) Inflammatory bowel disease ( 23128233) Metabolite levels ( 22916037) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		28 interacting genes: ATIC C17orf50 C22orf39 CEMP1 CRCT1 CXCL5 CYSRT1 DEFB112 FBXO34 FHL3 HOXA1 KRTAP10-8 KRTAP11-1 KRTAP19-2 LCE1A LCE1C LCE3A LCE5A MEOX2 NR4A3 OTX1 PPARA RIPK4 SPATA3 TRIM42 TYRO3 YPEL3 ZNF20	20 interacting genes: ACKR1 ACTN3 ALPP CCL11 CCL20 CXCL1 CXCL14 CXCL2 CXCL3 CXCR1 CXCR2 EFEMP2 FBLN1 GRN MEOX2 MGAT5B MMP9 NOTCH2NLA VWC2L XCL2
Entrez ID		402117	6374
HPRD ID		19160	08976
Ensembl ID		ENSG00000174453	ENSG00000163735
Uniprot IDs		B2RUY7 B7ZW27	P42830 Q6I9S7
PDB IDs			2MGS
Enriched GO Terms of Interacting Partners?
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