CENPP and POLR3K

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CENPP	POLR3K
Description		centromere protein P	RNA polymerase III subunit K
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Nucleus Nucleoplasm Nucleolus Cytosol	Nucleoplasm RNA Polymerase III Complex Nucleolus Cytosol
	Molecular Function	Protein Binding	Nucleic Acid Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Zinc Ion Binding
	Biological Process	CENP-A Containing Nucleosome Assembly	Transcription By RNA Polymerase III Termination Of RNA Polymerase III Transcription TRNA 3'-trailer Cleavage Innate Immune Response Defense Response To Virus
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Cytosolic sensors of pathogen-associated DNA RNA Polymerase III Chain Elongation RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) End-stage renal disease ( 29885931) HDL cholesterol levels ( 32203549) Height ( 28552196 31562340) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30224653 30578418) Triglyceride levels ( 32203549) Urate levels ( 31578528) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Body mass index ( 26426971) Mean corpuscular volume ( 32888494) Red blood cell traits ( 23446634)
Interacting Genes		27 interacting genes: ATP6V0D2 BACH2 C2orf88 CCDC33 CCDC85B CENPO CEP44 GOLGA2 HAUS1 KIAA1328 KLC3 LMNA MBD3 NHLH1 NTAQ1 PKNOX2 POLR3K RNF126 RPIA SERTAD3 STXBP1 SYCE1L TEX11 TOX2 USHBP1 ZNF341 ZNF765	3 interacting genes: CENPP SDCBP TRIM69
Entrez ID		401541	51728
HPRD ID		17989	16187
Ensembl ID		ENSG00000188312	ENSG00000161980
Uniprot IDs		Q6IPU0 Q7Z672	Q9Y2Y1
PDB IDs			7A6H 7AE1 7AE3 7AEA 7AST 7D58 7D59
Enriched GO Terms of Interacting Partners?
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