ARHGDIG and TACC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ARHGDIG	TACC3
Description		Rho GDP dissociation inhibitor gamma	transforming acidic coiled-coil containing protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle	Spindle Pole Cytoplasm Cytosol Centriolar Satellite Intracellular Membrane-bounded Organelle Mitotic Spindle
	Molecular Function	Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding	Protein Binding
	Biological Process	Blastocyst Hatching Negative Regulation Of Cell Adhesion Rho Protein Signal Transduction Regulation Of Protein Localization Regulation Of Catalytic Activity	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Metaphase/anaphase Transition Of Mitotic Cell Cycle Cell Population Proliferation Cerebral Cortex Development Cell Division Regulation Of Mitotic Spindle Organization Microtubule Cytoskeleton Organization Involved In Mitosis
Pathways		RHOB GTPase cycle CDC42 GTPase cycle RHOH GTPase cycle RHOG GTPase cycle	NOTCH3 Activation and Transmission of Signal to the Nucleus Negative regulation of NOTCH4 signaling
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Bladder cancer ( 24163127 20972438) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Hip circumference adjusted for BMI ( 34021172) Mean spheric corpuscular volume ( 32888494) Subcortical volume (MOSTest) ( 32665545) Urinary bladder cancer ( 20348956)
Interacting Genes		12 interacting genes: AGTR1 BICRAL CDC42 CEP170P1 KXD1 MED10 RAC1 RHOA RHOB RHOG RHOH TACC3	30 interacting genes: AKAP9 ARHGDIG ARNT ARNT2 ASPSCR1 AURKA BEX2 BEX3 C2CD6 CCHCR1 CDC20B CDKL5 CIB3 CLIP4 EIF3C GDF15 IQCD KAT2A KIZ KLC1 KLHL38 NDEL1 NOD2 NUP54 RNF20 SNX20 SPATA18 TBC1D22B TTF2 VPS37C
Entrez ID		398	10460
HPRD ID		04163	05601
Ensembl ID		ENSG00000242173	ENSG00000013810
Uniprot IDs		F1T0H7 Q99819	Q9Y6A5
PDB IDs			5LXN 5LXO 5ODS 5ODT
Enriched GO Terms of Interacting Partners?
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