LDHA and LDHB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LDHA	LDHB
Description		lactate dehydrogenase A	lactate dehydrogenase B
Image
GO Annotations	Cellular Component	Nucleus Cytosol Membrane Extracellular Exosome	Cytoplasm Mitochondrial Inner Membrane Cytosol Membrane Membrane Raft Extracellular Exosome
	Molecular Function	L-lactate Dehydrogenase Activity Protein Binding Kinase Binding Identical Protein Binding Cadherin Binding NAD Binding	L-lactate Dehydrogenase Activity Protein Binding Identical Protein Binding
	Biological Process	Response To Hypoxia Lactate Metabolic Process Glycolytic Process Response To Nutrient Response To Xenobiotic Stimulus Response To Glucose NAD Metabolic Process Response To Hydrogen Peroxide Positive Regulation Of Apoptotic Process Response To Estrogen Post-embryonic Animal Organ Development Response To CAMP	Carbohydrate Metabolic Process Carboxylic Acid Metabolic Process
Pathways		Pyruvate metabolism	Pyruvate metabolism
Drugs		NADH Etheno-NAD Nicotinamide Oxamic Acid Stiripentol Copper Artenimol	NADH 4-Hydroxy-1,2,5-oxadiazole-3-carboxylic acid Oxamic Acid Stiripentol Artenimol
Diseases
GWAS		Amyloid A serum levels ( 21124955) Serum metabolite levels ( 33031748)	Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		20 interacting genes: ABCC9 ACD DUX4 DYNLL1 FGFR1 GSK3A HNRNPD HULC KCNJ11 LDHB MAPK10 NDRG1 PCNA POT1 PTPRF TERF1 TINF2 UPF2 XRN1 YWHAQ	11 interacting genes: CKS1B CKS2 LDHA MYCBP2 OGT PEX5 POT1 PTPRF SDCBP SUMO4 TERF1
Entrez ID		3939	3945
HPRD ID		01025	01026
Ensembl ID		ENSG00000134333	ENSG00000111716
Uniprot IDs		P00338 V9HWB9	A0A5F9ZHM4 P07195 Q5U077
PDB IDs		1I10 4AJP 4JNK 4L4R 4L4S 4M49 4OJN 4OKN 4QO7 4QO8 4QSM 4QT0 4R68 4R69 4RLS 4ZVV 5IXS 5IXY 5W8H 5W8I 5W8J 5W8K 5W8L 5ZJD 5ZJE 5ZJF 6BAD 6BAG 6BAX 6BAZ 6BB0 6BB1 6BB2 6BB3 6MV8 6MVA 6Q0D 6Q13 6SBU 6SBV 6ZZR	1I0Z 1T2F
Enriched GO Terms of Interacting Partners?
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