KRTAP5-4 and BAG5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KRTAP5-4	BAG5
Description		keratin associated protein 5-4	BAG cochaperone 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Nucleus Cytoplasm Mitochondrion Cytosol Membrane Inclusion Body Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Adenyl-nucleotide Exchange Factor Activity Protein Binding Protein Kinase Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Chaperone Binding
	Biological Process		Protein Folding Golgi Organization Negative Regulation Of Neuron Projection Development Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Stabilization Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Protein Refolding Neuron Death Regulation Of Inclusion Body Assembly Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways		Keratinization	Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS			Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Broad depression or schizophrenia ( 30626913) Depression ( 29700475) Schizophrenia ( 25056061)
Interacting Genes		36 interacting genes: ADAMTSL4 BAG5 CATSPER1 CRCT1 CREB5 CRY2 CYSRT1 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP11-1 KRTAP5-2 KRTAP5-9 KRTAP9-2 KRTAP9-3 LCE1B LCE1C LCE1D LCE1E LCE1F LCE2C LCE3A LCE3B LCE3C LCE4A LCE5A MEOX2 NBPF19 NOTCH2NLA NUFIP2 PLEKHF2 POU4F2 RGS17 SMCP UBE2I	25 interacting genes: ANXA3 ATP5MJ BANP CDCA7L CIRBP CREBBP DES EFEMP1 FAM118B GOLGA6A IGHG4 JMJD6 KASH5 KRTAP5-4 LRRK1 MAD1L1 PINK1 PRKN SIVA1 SNCA STUB1 THAP1 TP53 TRIM27 VCP
Entrez ID		387267	9529
HPRD ID		12396	04862
Ensembl ID		ENSG00000241598	ENSG00000166170
Uniprot IDs		A8MUN0 Q6L8H1	A0A024R6M6 Q9UL15
PDB IDs			2D9D 3A8Y
Enriched GO Terms of Interacting Partners?
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