KRTAP5-3 and RGS17

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KRTAP5-3	RGS17
Description		keratin associated protein 5-3	regulator of G protein signaling 17
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Nucleus Cytoplasm Plasma Membrane Neuron Projection Synapse
	Molecular Function	Protein Binding	GTPase Activity GTPase Activator Activity Protein Binding
	Biological Process		Response To Amphetamine G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Catalytic Activity
Pathways		Keratinization	G alpha (q) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events
Drugs		Beta-D-Glucose
Diseases
GWAS			Adult body size ( 32376654) Alcohol dependence ( 26365420) Apolipoprotein A1 levels ( 32203549) Bacterial meningitis ( 31092817) Body mass index ( 28892062) Cuneus cortex volume ( 31530798) Diastolic blood pressure ( 30224653) Fasting glucose ( 33402679 34059833) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels ( 32203549) High density lipoprotein cholesterol levels ( 29083408) Lipoprotein (a) levels ( 26377243) Morning person ( 30696823) Pneumococcal meningitis ( 31092817) Prostate cancer ( 23535732) Triglyceride levels ( 32203549) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		43 interacting genes: ADAMTSL4 CATSPER1 CRCT1 CYSRT1 ECM1 FBXO34 FUCA2 GLRX3 HOXA1 KPRP KRTAP1-3 KRTAP1-5 KRTAP10-8 KRTAP11-1 KRTAP15-1 KRTAP4-2 KRTAP5-1 KRTAP5-9 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1D LCE1F LCE2C LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 MEOX2 NBPF19 NOTCH2NLA NR4A3 NUFIP2 OTX1 POU4F2 RAMP3 RGS17 SMCP	43 interacting genes: ADRB2 AQP1 BOLA2 BOLA2B CHRD CRCT1 CREB5 DHX37 GNAI1 GNAI3 HOXA1 HSD3B7 KRTAP4-11 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 LCE1A LCE1B LCE1D LCE1E LCE2A LCE2B LCE2C LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A NUFIP2 OSTM1 OTX1 PTGER3 RABEP1 RBBP8 RPL10A SLC39A7 SMCP STUB1 TBC1D16 VASN
Entrez ID		387266	26575
HPRD ID		12395	06223
Ensembl ID		ENSG00000196224	ENSG00000091844
Uniprot IDs		Q6L8H2	Q9UGC6
PDB IDs			1ZV4 6AM3
Enriched GO Terms of Interacting Partners?
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