KRT16 and CDK18

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KRT16	CDK18
Description		keratin 16	cyclin dependent kinase 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Cytoskeleton Intermediate Filament Extracellular Exosome	Cellular_component Nucleus Cytoplasm
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Morphogenesis Of An Epithelium Inflammatory Response Cytoskeleton Organization Aging Keratinocyte Differentiation Negative Regulation Of Cell Migration Keratinization Hair Cycle Innate Immune Response Intermediate Filament Cytoskeleton Organization Keratinocyte Migration Establishment Of Skin Barrier	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Protein Phosphorylation Regulation Of Cell Cycle
Pathways		Keratinization Formation of the cornified envelope
Drugs		Zinc Zinc acetate
Diseases
GWAS			Coronary artery disease in type 1 diabetes ( 29695241)
Interacting Genes		56 interacting genes: AMOT ARFIP2 C1orf109 C1orf216 CARD9 CCDC146 CCDC17 CCHCR1 CCNC CDK18 CYTH4 EPM2AIP1 GAS8 GNG10 HGS KIFC3 KLC4 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT78 KRT79 KRT8 KRT80 KRT81 KRT83 KRT85 KRT86 LMO1 LNX1 MBD3 PKN1 POLL PPP1R18 PRKAA2 PRPH PUS10 SEMA4C SGF29 SMARCD1 SMARCE1 SNAPIN TCHP TSG101 TTC23 TXLNB USHBP1	58 interacting genes: AK8 APP BLZF1 CBY2 CCDC102B CCDC125 CCDC85B CCDC88B CCND3 CCNDBP1 CCNK CEP76 DNAH2 EYA2 FSD2 GOLGA2 GOLGA6L9 GORASP2 HAP1 HMBOX1 HOMER3 HOOK2 INCA1 KIFC3 KRT15 KRT16 KRT31 KRT34 KRT40 KRT75 KRT86 LZTS2 MAD1L1 MID2 MIPOL1 MTUS2 NUTM1 PIBF1 PNMA1 PPFIA1 PTPRC RABEP1 REL SEC23A TRAF1 TRAF2 TRIM27 TRIM50 TRIM54 TSGA10 TTC23 VPS28 VPS52 YWHAQ ZNF426 ZNF438 ZNF774 ZRANB1
Entrez ID		3868	5129
HPRD ID		01018	01354
Ensembl ID		ENSG00000186832	ENSG00000117266
Uniprot IDs		P08779	A0A024R980 A0A024R996 Q07002 Q59G02
PDB IDs
Enriched GO Terms of Interacting Partners?
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