KIF22 and SVIL

Number of citations of the paper that reports this interaction (PubMedID 20309963)
28

Data Source:
BioGRID (two hybrid)

		KIF22	SVIL
Description		kinesin family member 22	supervillin
Image
GO Annotations	Cellular Component	Kinetochore Chromatin Nucleus Cytosol Kinesin Complex Microtubule Nuclear Speck Mitotic Spindle	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Midbody Cleavage Furrow Microtubule Minus-end Cell Projection Costamere
	Molecular Function	DNA Binding Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP Hydrolysis Activity	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Actin Filament Binding
	Biological Process	Mitotic Cell Cycle DNA Repair Microtubule-based Movement Sister Chromatid Cohesion Mitotic Metaphase Plate Congression Metaphase Plate Congression	Skeletal Muscle Tissue Development Actin Polymerization Or Depolymerization Positive Regulation Of Cytokinesis Actin Filament Severing Barbed-end Actin Filament Capping
Pathways		MHC class II antigen presentation COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Red blood cell traits ( 23222517)	Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Bone fracture in osteoporosis ( 28580392) Dilated cardiomyopathy ( 33495596) Dilated cardiomyopathy (MTAG) ( 33495596) Estimated glomerular filtration rate ( 31152163) Lung function (FEV1/FVC) ( 28166213) Metabolite levels ( 23823483) Neurofibrillary tangles ( 25188341) Normalized brain volume ( 19010793) Platelet thrombus formation ( 22550155) Plateletcrit ( 32888494)
Interacting Genes		6 interacting genes: ATXN1 GDF9 IMMT PJA1 SIAH1 SVIL	36 interacting genes: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF22 KIFC3 KMT2A KRT18 LMNA LMNB2 LUC7L2 MIF4GD MPHOSPH9 MRTFB NME2 NR3C1 ODF2 P2RX7 PAN3 PCNX3 PPARG SH3PXD2A SLAMF7 STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG
Entrez ID		3835	6840
HPRD ID		04445	04992
Ensembl ID		ENSG00000079616	ENSG00000197321
Uniprot IDs		A0A024R632 B7Z9T5 Q14807	A0A6I8PIX7 O95425 Q569J5
PDB IDs		2EDU 6NJE	2K6M 2K6N
Enriched GO Terms of Interacting Partners?
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