KIR2DL3 and BTN2A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KIR2DL3	BTN2A2
Description		killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3	butyrophilin subfamily 2 member A2
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Antigen Binding Protein Binding Signaling Receptor Activity Identical Protein Binding	Signaling Receptor Binding Protein Binding
	Biological Process	Immune Response	Regulation Of Cytokine Production Negative Regulation Of Cytokine Production Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Activated T Cell Proliferation T Cell Receptor Signaling Pathway
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) General cognitive ability ( 29844566) Headache ( 29397368) Hip circumference adjusted for BMI ( 34021172) Intelligence (MTAG) ( 29326435) Liver iron content ( 34128465) Neurociticism ( 29500382) Refractive error ( 32231278) Schizophrenia ( 19571809) Smoking initiation ( 33082346) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		64 interacting genes: ADGRE2 AGTRAP AIG1 ANKRD46 APOA2 APOD APP AQP10 ASGR1 ATP6V0E1 BMP10 BRICD5 BTN2A2 C3orf52 CDIPT CISD2 CLDN19 CLN6 COQ9 CXCL16 CXCL9 CYB5B CYBC1 EMD FAM209A FAM3C FUNDC2 GAST GJA8 GPR108 GPX8 HLA-C IFITM3 INSIG2 ITGAM JAGN1 KTN1 LAT LCK LEUTX LHFPL5 NINJ2 NRM NSG1 OLFM4 PLN PLPPR2 PTPN6 RNF152 RTP2 SEC22B SLC38A7 SMIM1 SNORC THBD TMEM218 TMEM222 TMEM243 TMEM86B TMEM97 TRAF3IP3 UPK1B UPK2 VAMP5	42 interacting genes: AQP6 BIK CD53 CD79A CISD2 CREB3 EBP ELOVL4 EMP1 ERGIC3 EVI2B FAM209A FATE1 FFAR2 GJB3 GPR42 GPRC5D GPX8 HSD3B7 KIR2DL3 LHFPL5 LMNA MRM3 MUC1 PEX12 PSMA3 SEC11C SLC10A6 SLC14A1 SLC16A2 SLC1A3 SLC30A4 SLC39A2 SPNS3 STX1A SYT1 TMEM14B TMEM179B TMEM237 TMEM31 TMEM52B TMX2
Entrez ID		3804	10385
HPRD ID		10383	12545
Ensembl ID		ENSG00000243772	ENSG00000124508
Uniprot IDs		E3NZD8 P43628	A0A024R038 Q8WVV5
PDB IDs		1B6U 6PAG
Enriched GO Terms of Interacting Partners?
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