ARF4 and APBA3

Number of citations of the paper that reports this interaction (PubMedID 12842896)
42

Data Source:
BioGRID (two hybrid)

		ARF4	APBA3
Description		ADP ribosylation factor 4	amyloid beta precursor protein binding family A member 3
Image
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Ruffle Membrane Dendritic Spine Extracellular Exosome Glutamatergic Synapse	Cytoplasm Plasma Membrane Dendritic Spine Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activity Guanyl-nucleotide Exchange Factor Activity Epidermal Growth Factor Receptor Binding Protein Binding GTP Binding	Amyloid-beta Binding Enzyme Inhibitor Activity Protein Binding Enzyme Binding
	Biological Process	Protein ADP-ribosylation Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Epidermal Growth Factor Receptor Signaling Pathway Brain Development Learning Vesicle-mediated Transport Cell Migration Activation Of Phospholipase D Activity Negative Regulation Of Apoptotic Process Apical Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Transcription By RNA Polymerase II Response To Axon Injury Cilium Assembly Dendritic Spine Development Protein Localization To Cilium Regulation Of Postsynapse Organization Regulation Of Reactive Oxygen Species Metabolic Process	In Utero Embryonic Development Chemical Synaptic Transmission Regulation Of Gene Expression Protein Transport Negative Regulation Of Catalytic Activity
Pathways		VxPx cargo-targeting to cilium VxPx cargo-targeting to cilium COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Neurexins and neuroligins
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS			Serum alkaline phosphatase levels ( 33547301)
Interacting Genes		16 interacting genes: ADRB2 APBA1 APBA2 APBA3 COPS3 EGFR HNRNPD IKBKG ITIH1 PTEN RAB11FIP3 RCHY1 RHOA SDCBP2 SIRPA SUMO2	10 interacting genes: APP ARF3 ARF4 AZI2 BCR BDNF EGFR GPX4 TANK TBKBP1
Entrez ID		378	9546
HPRD ID		03107	05038
Ensembl ID		ENSG00000168374	ENSG00000011132
Uniprot IDs		P18085	O96018
PDB IDs		1Z6X	2YT7 2YT8 5UWS
Enriched GO Terms of Interacting Partners?
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