SPATC1 and TUBG1

Number of citations of the paper that reports this interaction (PubMedID 15280373)
14

Data Source:
HPRD (in vitro)

		SPATC1	TUBG1
Description		spermatogenesis and centriole associated 1	tubulin gamma 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome	Pericentriolar Material Condensed Nuclear Chromosome Gamma-tubulin Complex Nucleus Cytoplasm Centrosome Centriole Spindle Polar Microtubule Cytosol Microtubule Cytoplasmic Microtubule Cell Leading Edge Ciliary Basal Body Apical Part Of Cell Recycling Endosome Non-motile Cilium Mitotic Spindle Microtubule
	Molecular Function		GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Identical Protein Binding
	Biological Process		Mitotic Sister Chromatid Segregation Meiotic Spindle Organization Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Mitotic Spindle Organization Cytoplasmic Microtubule Organization
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs			Vinblastine
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Brain morphology (MOSTest) ( 32665545) Fibrinogen levels ( 28107422) Mean corpuscular hemoglobin ( 29403010)	Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549)
Interacting Genes		3 interacting genes: CDC20 MROH5 TUBG1	35 interacting genes: APP BRCA1 CENPJ CNTN2 CTRL CUL4A DDX41 IKBKG KIF14 KRT18 KRT19 MARK4 NAPG NDE1 OGT PCNT PHB PIK3R1 PLK1 PXN RACGAP1 RACK1 RARA RASSF1 RND2 RNF19A RPGR SGCA SPATC1 TUBA1B TUBA3C TUBB4B TUBGCP3 TUBGCP4 WNT3
Entrez ID		375686	7283
HPRD ID		15433	01853
Ensembl ID		ENSG00000186583	ENSG00000131462
Uniprot IDs		A0A140VJV4 Q76KD6	P23258
PDB IDs			1Z5V 1Z5W 3CB2 6V5V 6V6S 7AS4
Enriched GO Terms of Interacting Partners?
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