KCNC1 and KCNH1

Number of citations of the paper that reports this interaction (PubMedID 12060745)
55

Data Source:
BioGRID (two hybrid)

		KCNC1	KCNH1
Description		potassium voltage-gated channel subfamily C member 1	potassium voltage-gated channel subfamily H member 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Integral Component Of Membrane Axon Axolemma Dendrite Membrane Neuronal Cell Body Membrane Calyx Of Held Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane	Nuclear Inner Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Dendrite Axolemma Early Endosome Membrane Perikaryon Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Postsynaptic Density Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Kinesin Binding Transmembrane Transporter Binding Voltage-gated Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding Protein Kinase Binding Cyclic Nucleotide Binding Identical Protein Binding Transmembrane Transporter Binding Protein-containing Complex Binding 14-3-3 Protein Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Potassium Ion Transport Response To Toxic Substance Response To Light Intensity Response To Auditory Stimulus Response To Amine Cerebellum Development Globus Pallidus Development Response To Potassium Ion Protein Homooligomerization Protein Tetramerization Cellular Response To Xenobiotic Stimulus Response To Fibroblast Growth Factor Potassium Ion Transmembrane Transport Regulation Of Presynaptic Membrane Potential Positive Regulation Of Voltage-gated Potassium Channel Activity Response To Nerve Growth Factor	Startle Response Potassium Ion Transport Myoblast Fusion Regulation Of Ion Transmembrane Transport Regulation Of Cell Population Proliferation Regulation Of Membrane Potential Phosphatidylinositol-mediated Signaling Cellular Response To Calcium Ion Potassium Ion Transmembrane Transport
Pathways		Voltage gated Potassium channels	Voltage gated Potassium channels
Drugs		Enflurane Promethazine Miconazole Dalfampridine	Enflurane Imipramine Astemizole Promethazine Miconazole
Diseases
GWAS		Body mass index ( 26426971) Night sleep phenotypes ( 27126917) Opioid sensitivity ( 24143882)	Blond vs. brown/black hair color ( 30531825) Bone mineral density (femoral neck) ( 27424934) Bone mineral density (spine) and age at menarche ( 26312577) Bone mineral density (total hip) ( 27424934) Cancer ( 27197191) Cholesterol ( 31902109) Circulating vasoactive peptide levels ( 23381795) Cobalt levels ( 26025379) Hematocrit ( 32888494) Hemoglobin ( 32888494)
Interacting Genes		7 interacting genes: ANK3 KCNG3 KCNH1 KCNV2 LPAR3 TMBIM6 TRARG1	10 interacting genes: ALG10 CALM1 FASTKD5 KCNB1 KCNC1 KCNF1 KCNH5 MTDH NTAQ1 SDCBP
Entrez ID		3746	3756
HPRD ID		15936	04492
Ensembl ID		ENSG00000129159	ENSG00000143473
Uniprot IDs		P48547 Q3KNS8	O95259
PDB IDs			5J7E
Enriched GO Terms of Interacting Partners?
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