TMEM179B and BTN2A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TMEM179B	BTN2A2
Description		transmembrane protein 179B	butyrophilin subfamily 2 member A2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus Plasma Membrane Integral Component Of Membrane Nuclear Speck Secretory Granule Membrane Azurophil Granule Membrane Ficolin-1-rich Granule Membrane	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	Signaling Receptor Binding Protein Binding
	Biological Process		Regulation Of Cytokine Production Negative Regulation Of Cytokine Production Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Activated T Cell Proliferation T Cell Receptor Signaling Pathway
Pathways		Neutrophil degranulation	Butyrophilin (BTN) family interactions
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) General cognitive ability ( 29844566) Headache ( 29397368) Hip circumference adjusted for BMI ( 34021172) Intelligence (MTAG) ( 29326435) Liver iron content ( 34128465) Neurociticism ( 29500382) Refractive error ( 32231278) Schizophrenia ( 19571809) Smoking initiation ( 33082346) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		47 interacting genes: ADIPOQ BTN2A2 C1QL4 C2CD2L C3orf52 CCDC167 CCL3L3 CCL4 CCL4L2 CD68 CLCA4 CLCN7 CLDN1 CLDN6 CTXN3 CYB561 DERL3 ERGIC3 FAM163A FATE1 FCER1G FXYD3 GALNT15 GKN1 GPR151 GUCA2A IGFBP5 KRTAP12-2 KTN1 LRP10 LYG1 MARCHF2 MFSD5 MFSD6 PLN SERP2 SLC1A1 SLC22A1 SLC52A1 STX8 TM4SF19 TMEM14A TMEM236 TMEM237 TMEM242 TMEM47 TRARG1	42 interacting genes: AQP6 BIK CD53 CD79A CISD2 CREB3 EBP ELOVL4 EMP1 ERGIC3 EVI2B FAM209A FATE1 FFAR2 GJB3 GPR42 GPRC5D GPX8 HSD3B7 KIR2DL3 LHFPL5 LMNA MRM3 MUC1 PEX12 PSMA3 SEC11C SLC10A6 SLC14A1 SLC16A2 SLC1A3 SLC30A4 SLC39A2 SPNS3 STX1A SYT1 TMEM14B TMEM179B TMEM237 TMEM31 TMEM52B TMX2
Entrez ID		374395	10385
HPRD ID		14186	12545
Ensembl ID		ENSG00000185475	ENSG00000124508
Uniprot IDs		Q7Z7N9	A0A024R038 Q8WVV5
PDB IDs
Enriched GO Terms of Interacting Partners?
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