ITGB6 and FLNB

Number of citations of the paper that reports this interaction (PubMedID 11807098)
41

Data Source:
BioGRID (two hybrid)

		ITGB6	FLNB
Description		integrin subunit beta 6	filamin B
Image
GO Annotations	Cellular Component	Nucleoplasm Centrosome Plasma Membrane Focal Adhesion Integrin Complex External Side Of Plasma Membrane Cell Surface Cell Junction Integrin Alphav-beta6 Complex Receptor Complex	Stress Fiber Nucleus Cytoplasm Cytosol Plasma Membrane Brush Border Focal Adhesion Cell Cortex Actin Cytoskeleton Integral Component Of Membrane Z Disc Neuron Projection Neuronal Cell Body Phagocytic Vesicle Extracellular Exosome
	Molecular Function	Virus Receptor Activity Integrin Binding Protein Binding Signaling Receptor Activity	RNA Binding Actin Binding Protein Binding Identical Protein Binding Cadherin Binding Actin Filament Binding
	Biological Process	Cell Morphogenesis Inflammatory Response Immune Response Cell Adhesion Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Response To Virus Cell Migration Cell Adhesion Mediated By Integrin Wound Healing Surfactant Homeostasis Skin Development Viral Entry Into Host Cell Lung Alveolus Development Phospholipid Homeostasis Hard Palate Development Bone Development SMAD Protein Signal Transduction Bronchiole Development Langerhans Cell Differentiation Enamel Mineralization Cellular Response To Ionizing Radiation Transforming Growth Factor Beta Production Regulation Of Transforming Growth Factor Beta Activation	Keratinocyte Development Epithelial Cell Morphogenesis Signal Transduction Skeletal Muscle Tissue Development Actin Cytoskeleton Organization Cellular Response To Interferon-gamma
Pathways		Elastic fibre formation Molecules associated with elastic fibres Integrin cell surface interactions ECM proteoglycans	ISG15 antiviral mechanism
Drugs
Diseases
GWAS		Asthma (childhood onset) ( 31036433) Eosinophil counts ( 32888494) Haemorrhoidal disease ( 33888516) Hematocrit ( 32888494) Hemoglobin ( 32888494) Idiopathic membranous nephropathy ( 21323541) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Tourette syndrome ( 30818990) Type 2 diabetes ( 20418489) Waist circumference adjusted for body mass index ( 25673412)	Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) ( 23648065) Body shape index ( 34021172) Eating disorders (purging via substances) ( 23568457) Glaucoma (low intraocular pressure) ( 33627673) Gut microbiota (bacterial taxa) ( 27723756) Height ( 31217584 33713608) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Lymphocyte counts ( 32888494) Neutrophil count ( 32888494) Optic cup area ( 25631615 31798171 28073927) Pulse pressure ( 30578418) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Systemic sclerosis ( 31672989) Vertical cup-disc ratio ( 28073927) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Waist circumference adjusted for body mass index ( 34021172) White blood cell count ( 32888494)
Interacting Genes		8 interacting genes: FHL2 FLNA FLNB FN1 ITGAV MAPK1 TGFB1 VTN	23 interacting genes: ASB2 ATF7IP ERBB2 FBLIM1 FLNA FXR1 GP1BA HSPB1 ITGB1 ITGB3 ITGB6 MLH1 MYBPC2 NPHP1 PLEKHO1 PSEN1 PSEN2 RAD21 SMURF2 SUMO2 TRIM55 TSC22D2 TSHR
Entrez ID		3694	2317
HPRD ID		00947	04543
Ensembl ID		ENSG00000115221	ENSG00000136068
Uniprot IDs		A0A087WXP3 B4E2B8 E9PEE8 P18564	O75369
PDB IDs		1LH9 4UM8 4UM9 5FFG 5FFO 5NEM 5NER 5NET 5NEU	2DI8 2DI9 2DIA 2DIB 2DIC 2DJ4 2DLG 2DMB 2DMC 2E9I 2E9J 2EE6 2EE9 2EEA 2EEB 2EEC 2EED 2WA5 2WA6 2WA7 3FER 4B7L 5DCP
Enriched GO Terms of Interacting Partners?
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