EIF3E and COPS7B

Number of citations of the paper that reports this interaction (PubMedID 12220626)
27

Data Source:
HPRD (in vivo)

		EIF3E	COPS7B
Description		eukaryotic translation initiation factor 3 subunit E	COP9 signalosome subunit 7B
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex PML Body Eukaryotic 48S Preinitiation Complex Extracellular Exosome Eukaryotic Translation Initiation Factor 3 Complex, EIF3e	Nucleoplasm Cytosol COP9 Signalosome
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding Cadherin Binding Protein N-terminus Binding	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Regulation Of Translational Initiation Positive Regulation Of Translation Negative Regulation Of Translational Initiation Positive Regulation Of MRNA Binding	Protein Deneddylation COP9 Signalosome Assembly
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Coffee consumption ( 31046077) Dupuytren's disease ( 28886342 21732829) Heel bone mineral density ( 30598549) Macular thickness ( 30535121) Male-pattern baldness ( 28196072) Ossification of the posterior longitudinal ligament of the spine ( 25064007)	Height ( 18391951)
Interacting Genes		34 interacting genes: ATM C4orf19 COPS6 COPS7A COPS7B COPS8 DDX24 DRC3 EIF3C EIF3L EIF4ENIF1 EPAS1 EPN2 GPAA1 GPBP1L1 HAP1 IFIT1 ISCA2 KPRP LINC01554 MAPK1IP1L MIIP MRNIP NDRG1 NSF OGT PRRC2A RUNDC3A SHBG SMAD9 TRIM27 TRIM55 TRIM63 ZNF48	11 interacting genes: APP BEX5 COPS2 COPS3 COPS4 COPS5 COPS6 EIF3E GPS1 NMI PMF1
Entrez ID		3646	64708
HPRD ID		03734	09889
Ensembl ID		ENSG00000104408	ENSG00000144524
Uniprot IDs		P60228	A0A024R471 A0A024R478 A0A087X1P5 J3KQ34 J3KQ41 Q6ZTQ7 Q9H9Q2
PDB IDs		3J8B 3J8C 6FEC 6YBD 6ZMW 6ZON 6ZP4 6ZVJ 7A09	6R6H 6R7F 6R7H 6R7I 6R7N
Enriched GO Terms of Interacting Partners?
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