IMPDH2 and RBM15B

		IMPDH2	RBM15B
Description		inosine monophosphate dehydrogenase 2	RNA binding motif protein 15B
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Peroxisomal Membrane Cytosol Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Nucleus Nuclear Envelope Nucleoplasm Nucleolus Nuclear Speck RNA N6-methyladenosine Methyltransferase Complex
	Molecular Function	Nucleotide Binding DNA Binding RNA Binding IMP Dehydrogenase Activity Protein Binding Identical Protein Binding Metal Ion Binding	RNA Binding MRNA Binding Protein Binding
	Biological Process	GMP Biosynthetic Process GTP Biosynthetic Process Circadian Rhythm Lymphocyte Proliferation Retina Development In Camera-type Eye Cellular Response To Interleukin-4	Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Methylation MRNA Processing MRNA Export From Nucleus Nucleocytoplasmic Transport RNA Splicing Dosage Compensation By Inactivation Of X Chromosome Negative Regulation Of Transcription, DNA-templated
Pathways		Neutrophil degranulation Purine ribonucleoside monophosphate biosynthesis Potential therapeutics for SARS
Drugs		NADH Mycophenolate mofetil Ribavirin Mycophenolic acid Mercaptopurine Selenazole-4-carboxyamide-adenine dinucleotide 6-Chloropurine Riboside, 5'-Monophosphate Inosinic Acid VX-148
Diseases
GWAS		Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)	Allergic disease (asthma, hay fever or eczema) ( 29679657) Apolipoprotein A1 levels ( 33730874)
Interacting Genes		32 interacting genes: AGR2 AKT1 ALS2 AMT APIP APPL1 ATXN2 ATXN7 C1S CEACAM5 CLK1 CPLANE2 DCAF1 DNASE1L3 FBXL7 FXR1 FXR2 IL1F10 KLF7 OGT PIAS4 POU6F2 PRMT1 PXMP2 PXN RAD54L2 RBM15B STAT3 SUMO2 SUMO4 TRAF2 UBQLN4	14 interacting genes: AMT ATP6V0D2 CDC23 DVL3 EGR2 ERBB2 IMPDH2 ITIH1 NAV2 NXF1 PTEN SRPK2 TNNC1 TRIM54
Entrez ID		3615	29890
HPRD ID		00895	11486
Ensembl ID		ENSG00000178035	ENSG00000259956
Uniprot IDs		A0A384N6C2 P12268	Q8NDT2
PDB IDs		1B3O 1NF7 1NFB 6I0M 6I0O 6U8E 6U8N 6U8R 6U8S 6U9O 6UA2 6UA4 6UA5 6UAJ 6UC2 6UDO 6UDP 6UDQ
Enriched GO Terms of Interacting Partners?
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