SERINC2 and SLC29A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SERINC2	SLC29A2
Description		serine incorporator 2	solute carrier family 29 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Integral Component Of Membrane Extracellular Exosome	Nucleolus Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Nuclear Membrane Presynapse
	Molecular Function		Neurotransmitter Transmembrane Transporter Activity Nucleoside Transmembrane Transporter Activity Purine Nucleoside Transmembrane Transporter Activity Uridine Transmembrane Transporter Activity
	Biological Process	Phosphatidylserine Metabolic Process Sphingolipid Metabolic Process Positive Regulation Of CDP-diacylglycerol-serine O-phosphatidyltransferase Activity Positive Regulation Of Serine C-palmitoyltransferase Activity	Neurotransmitter Uptake Neurotransmitter Transport Adenine Transport Guanine Transport Nucleoside Transport Purine Nucleoside Transmembrane Transport Uridine Transport Adenosine Transport Hypoxanthine Transport Thymine Transport Pyrimidine-containing Compound Transmembrane Transport Neurotransmitter Reuptake Transport Across Blood-brain Barrier Nucleoside Transmembrane Transport
Pathways		Serine biosynthesis	Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Drugs			Ethanol
Diseases
GWAS		Alcohol dependence ( 23455491) Body mass index ( 26426971) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Heart rate response to recovery post exercise (50 sec) ( 29497042) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)	Bipolar disorder ( 21926972) Serum metabolite levels ( 33031748) Serum uric acid levels ( 32514006)
Interacting Genes		16 interacting genes: C4orf3 CCDC167 GPX8 LAT MFF SEC22B SLC12A7 SLC29A2 SLC39A9 SMAGP TMEM14A TMEM167B TMEM239 TMEM42 TMEM54 TMEM86B	19 interacting genes: ALOX5AP CERS3 CERS4 CREB3 ERGIC3 GJA4 GPR152 LAPTM4B PLPP5 SERINC2 SLC10A1 SLC10A6 TMEM237 TMEM242 TMEM33 TMEM86B TMX2 UBQLN1 UBQLN2
Entrez ID		347735	3177
HPRD ID		15481	03662
Ensembl ID		ENSG00000168528	ENSG00000174669
Uniprot IDs		Q96IM8 Q96SA4	G5E943 Q14542 Q96FB2
PDB IDs
Enriched GO Terms of Interacting Partners?
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