FAM174A and FKBP8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FAM174A	FKBP8
Description		family with sequence similarity 174 member A	FKBP prolyl isomerase 8
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Mitochondrion Endoplasmic Reticulum Cytosol Membrane Integral Component Of Endoplasmic Reticulum Membrane Mitochondrial Membrane Protein-containing Complex
	Molecular Function	Protein Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Identical Protein Binding Protein Folding Chaperone Metal Ion Binding Disordered Domain Specific Binding
	Biological Process		Protein Peptidyl-prolyl Isomerization Cell Fate Specification Negative Regulation Of Protein Phosphorylation Protein Folding Apoptotic Process Smoothened Signaling Pathway Regulation Of Gene Expression Dorsal/ventral Neural Tube Patterning Positive Regulation Of BMP Signaling Pathway Multicellular Organism Growth Intracellular Signal Transduction Camera-type Eye Development Negative Regulation Of Apoptotic Process
Pathways			Ub-specific processing proteases
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549)	Plasma parathyroid hormone levels ( 30134803) Urinary potassium excretion ( 31409800)
Interacting Genes		36 interacting genes: ANKRD46 BET1 BNIP1 C14orf180 C4orf3 CCDC167 CMTM7 DEFB127 ERG28 FKBP8 GIMAP1 GIMAP5 GOSR2 HMOX1 LCK PLLP PLPP6 RTP2 SEC22A SEC22B SERP1 SLC30A2 SMCO4 SMIM1 STX7 STX8 TMEM11 TMEM203 TMEM222 TMEM239 TMEM243 TMEM42 TMEM65 TREX1 VAMP3 VAPB	50 interacting genes: ANKMY2 ARHGEF5 ARL13B ATP13A2 BCL2 BCL2L1 BNIPL CD79A CIDEB CLCN1 CXCR2 CYB561 CYBRD1 EBP EGFR ELOVL4 ERBB2 ERGIC3 FAM174A FGF14 GPR37 JAGN1 MAPK14 MFSD14B MTOR OGT PEX12 PLN PPP3CA PSMC1 PSMD2 RETREG3 RHBDD2 RHEB SCN3B SHANK3 SLC10A6 SLC35A5 SLC35B1 SMO TERF1 TMEM14B TMEM254 TMEM31 TMEM43 TMEM45B TMEM80 TMX1 VHL ZFPL1
Entrez ID		345757	23770
HPRD ID		18260	05327
Ensembl ID		ENSG00000174132	ENSG00000105701
Uniprot IDs		Q8TBP5	A0A024R7P2 B2R8G6 Q14318
PDB IDs			2AWG 2D9F 2F2D 2MF9 3EY6 5MGX
Enriched GO Terms of Interacting Partners?
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