NOTO and NKX2-4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NOTO	NKX2-4
Description		notochord homeobox	NK2 homeobox 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromatin Cellular_component Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Molecular_function Protein Binding
	Biological Process	Heart Looping Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Embryonic Pattern Specification Dorsal/ventral Pattern Formation Neuron Differentiation Notochord Development Motile Cilium Assembly Regulation Of Cilium Assembly	Regulation Of Transcription By RNA Polymerase II Biological_process Cell Differentiation
Pathways
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435)	Adult body size ( 32376654) Autism spectrum disorder ( 30804558) Lupus nephritis in systemic lupus erythematosus ( 24925725) Metabolite levels ( 23823483)
Interacting Genes		31 interacting genes: ANKRD11 APOBEC1 BAG3 BANP BTF3 CCDC120 CEP19 CHAF1A EIPR1 ETV3L FAM9B FOXD2 FOXH1 GLYCTK HNRNPK IP6K3 KRT34 KRTAP19-7 KRTAP5-6 KRTAP6-1 KRTAP6-3 LDLRAP1 LRP10 MAGED1 MEIS2 NKX2-4 PIH1D2 POU4F2 SBK3 TTC23 UBTFL1	1 interacting genes: NOTO
Entrez ID		344022	644524
HPRD ID
Ensembl ID		ENSG00000214513	ENSG00000125816
Uniprot IDs		A8MTQ0	Q9H2Z4
PDB IDs
Enriched GO Terms of Interacting Partners?
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