ID1 and IFI16

Number of citations of the paper that reports this interaction (PubMedID 11940648)
24

Data Source:
HPRD (in vitro, in vivo)

		ID1	IFI16
Description		inhibitor of DNA binding 1, HLH protein	interferon gamma inducible protein 16
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Golgi Apparatus Centrosome	Nucleus Nucleoplasm Nucleolus Cytosol Membrane Nuclear Speck
	Molecular Function	Protein Binding Protein C-terminus Binding Identical Protein Binding Protein Dimerization Activity Protein N-terminus Binding Proteasome Binding Transcription Regulator Activity Transcription Regulator Inhibitor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded DNA Binding RNA Binding Protein Binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Brain Development Negative Regulation Of Transcription By Transcription Factor Localization Positive Regulation Of Gene Expression Cell Differentiation Neuron Differentiation Negative Regulation Of Protein Binding Positive Regulation Of Actin Filament Bundle Assembly Circadian Regulation Of Gene Expression Cell-abiotic Substrate Adhesion Negative Regulation Of Apoptotic Process Negative Regulation Of DNA Binding Negative Regulation Of DNA-binding Transcription Factor Activity Blood Vessel Endothelial Cell Migration Negative Regulation Of Endothelial Cell Differentiation Negative Regulation Of Transcription, DNA-templated Blood Vessel Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Negative Regulation Of Dendrite Morphogenesis Cellular Response To Epidermal Growth Factor Stimulus Negative Regulation Of Cold-induced Thermogenesis Regulation Of Vasculature Development Cellular Response To Peptide Cellular Response To Dopamine Cellular Response To Nerve Growth Factor Stimulus	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cytokine Production Activation Of Innate Immune Response Autophagy Inflammatory Response Regulation Of Autophagy Myeloid Cell Differentiation Monocyte Differentiation Positive Regulation Of Interleukin-1 Beta Production Cellular Response To Interferon-beta Regulation Of Gene Expression, Epigenetic Cellular Response To Glucose Starvation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Binding Negative Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Innate Immune Response Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus Cellular Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Activation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Cysteine-type Endopeptidase Activity
Pathways		Oncogene Induced Senescence NGF-stimulated transcription	STING mediated induction of host immune responses IRF3-mediated induction of type I IFN
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Systolic blood pressure ( 27841878)	Blood protein levels ( 29875488) C-reactive protein ( 22939635) Celiac disease or Rheumatoid arthritis ( 21383967) Lymphocyte percentage of white cells ( 32888494) Neutrophil count in HIV-infection ( 25884002) Neutrophil percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Periodontal disease-related phenotype (Socransky) ( 26962152)
Interacting Genes		27 interacting genes: AAR2 APPL1 ASCL3 ASXL1 CASK COPB1 DNMT3L ELK1 ELK4 GATA4 HES1 IFI16 IKBKG MSGN1 MYF5 MYF6 MYOD1 MYOG POFUT1 PSMD4 RUNX1T1 SUV39H1 TCF12 TCF3 TCF4 TRIM55 TRIM63	12 interacting genes: APP AR AURKA BRCA1 CSNK2A1 ID1 ID2 ID3 STING1 TP53 TP53BP1 TPR
Entrez ID		3397	3428
HPRD ID		08980	00969
Ensembl ID		ENSG00000125968	ENSG00000163565
Uniprot IDs		P41134	Q16666
PDB IDs			2OQ0 3B6Y 3RLN 3RLO 3RNU 4QGU
Enriched GO Terms of Interacting Partners?
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