KRTAP19-6 and FANCL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KRTAP19-6	FANCL
Description		keratin associated protein 19-6	FA complementation group L
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Nuclear Body Intracellular Membrane-bounded Organelle Fanconi Anaemia Nuclear Complex
	Molecular Function	Protein Binding	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process		DNA Repair Protein Monoubiquitination Cellular Response To DNA Damage Stimulus Gamete Generation Interstrand Cross-link Repair Regulation Of Cell Population Proliferation
Pathways		Keratinization	Fanconi Anemia Pathway
Drugs
Diseases
GWAS			Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 31453325 20935630) Body mass index variance ( 31453325) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Childhood absence epilepsy ( 30531953) Chronotype ( 30696823) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Daytime nap ( 33568662) Epilepsy ( 25087078 30531953) Feeling miserable ( 29500382) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Generalized epilepsy ( 30531953) HDL cholesterol levels ( 32203549) Hirschsprung disease ( 27702942) Initial pursuit acceleration ( 29064472) Irritable mood ( 29500382) Obesity ( 23563607) Pre-treatment viral load in HIV-1 infection ( 31219150) Response to selective serotonin reuptake inhibitors and depression ( 27622933) Schizophrenia ( 25056061 29483656) Smoking status (ever vs never smokers) ( 30643258) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Tea consumption ( 31046077) Triglyceride levels ( 32203549) Type 2 diabetes ( 30718926) Waist circumference ( 25673412) Waist-hip index ( 34021172) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		68 interacting genes: ATPAF2 BCAS2 C11orf16 C20orf85 C9orf24 CATSPER1 CCDC24 CCNK CERK CREB5 CRY2 CSKMT CYSRT1 DMRTB1 DTX2 ENKD1 FAM214B FANCL FNDC11 FOXH1 GPANK1 GUCD1 HOXA1 HSF4 INCA1 KIFC3 KPRP KRTAP12-4 KRTAP26-1 KRTAP6-3 KRTAP9-3 LASP1 LONRF1 MEIS2 MGAT5B MKRN3 MYOZ3 MYPOP NOC4L NTAQ1 OIP5 PATZ1 PLAC8 PLEKHN1 PLSCR3 PLSCR4 POU4F2 PPP1R32 PROP1 PSMB2 RBPMS2 RHOXF2 RUNX1T1 SLC25A18 SMN1 SMN2 SNRPB SNRPC SPAG8 TEKT4 TEKT5 TENT5B TFAP2D TSPYL6 VENTX VGLL3 VPS37C ZNF414	48 interacting genes: ACVR1 ANTKMT BMPR1B C19orf54 CADPS CERCAM CHCHD3 CTBP1 CTDSP1 CYB5R2 DDAH2 DOCK8 EIF4ENIF1 FAAP100 FANCB FANCD2 FANCF FANCI GATA1 GGN GRN HDHD3 HES1 HOXD4 ID2 IHO1 IKZF3 KIFC3 KRTAP11-1 KRTAP13-2 KRTAP19-6 LZTS2 METTL15 MORN3 PCNA RBM45 RIMBP3 RNF11 SCNM1 SNF8 SSX2IP TFCP2 TGFBR1 UBE2T UBE2W UFSP1 YPEL3 ZNF581
Entrez ID		337973	55120
HPRD ID		11210	06997
Ensembl ID		ENSG00000186925	ENSG00000115392
Uniprot IDs		A4FU57 Q3LI70	Q9NW38
PDB IDs			3ZQS 4CCG
Enriched GO Terms of Interacting Partners?
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