HOXD4 and ZMYND11

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		HOXD4	ZMYND11
Description		homeobox D4	zinc finger MYND-type containing 11
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cell Junction	Nucleus Nucleoplasm Chromosome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	Double-stranded DNA Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding Methylated Histone Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Anterior/posterior Pattern Specification Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis	Chromatin Organization Cell Cycle Regulation Of Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Transcription, DNA-templated Negative Regulation Of JNK Cascade Defense Response To Virus Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Male-pattern baldness ( 28196072) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Pelvic organ prolapse (moderate/severe) ( 26545240)	Malaria ( 31844061)
Interacting Genes		21 interacting genes: ASB8 CNOT7 CREBBP DEDD EP300 ETV4 FANCL HIPK1 HNRNPAB HOXB13 MEIS1 PBX1 PBX4 RNPS1 RXRG SNAI1 TIGD4 XRCC6 ZBTB32 ZMYND11 ZSCAN18	25 interacting genes: BMPR1A DYNLL1 E2F6 EMSY ETS2 EZH1 EZH2 H3-3A H3-4 HDAC1 HOXD4 LTBR MAGEC2 MYB NCOR1 PDLIM7 SMAD2 SMAD3 SMARCA4 SRPK1 TAB1 TCF20 TRAF3 TRAF6 ZHX1
Entrez ID		3233	10771
HPRD ID		00864	09830
Ensembl ID		ENSG00000170166	ENSG00000015171
Uniprot IDs		P09016	B7Z2J6 J3QKD2 Q15326 Q5BJG6 Q5UGI2
PDB IDs			4NS5 5HDA
Enriched GO Terms of Interacting Partners?
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