HNF4G and ZNF629

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HNF4G	ZNF629
Description		hepatocyte nuclear factor 4 gamma	zinc finger protein 629
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Cytosol Intercellular Bridge Mitotic Spindle	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Nuclear Receptor Activity Zinc Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Cell Differentiation Intracellular Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Regulation of gene expression in beta cells Nuclear Receptor transcription pathway
Drugs		Palmitic Acid
Diseases
GWAS		Adult body size ( 32376654) Attention function ( 29907492) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 26426971 28892062 25673413 20935630 28448500) Body mass index (age <50) ( 26426971) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body mass index in physically inactive individuals ( 28448500) Body mass index x sex x age interaction (4df test) ( 26426971) Body size at age 10 ( 32376654) Breast cancer ( 29059683 23535729) Chronotype ( 30696823) Estimated glomerular filtration rate ( 31152163) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Morning person ( 30696823) Number of sexual partners ( 30643258) Obesity ( 23563607) Pancreatic cancer ( 29422604) Pulse pressure ( 27841878) Red blood cell count ( 32888494) Serum uric acid levels ( 30993211 29403010) Systolic blood pressure ( 27841878) Urate levels ( 31985003 31578528 23263486) Waist circumference adjusted for body mass index ( 28552196)	Systemic lupus erythematosus ( 33272962)
Interacting Genes		16 interacting genes: COPS5 DNMT3L ELOC GAPDH HAX1 HLF NCOA1 NR0B2 NSD1 PNRC1 PNRC2 PRDX6 PSMC5 RANBP9 TNNI2 ZNF629	20 interacting genes: CCHCR1 CDR2L GAS8 GOLGA6L9 HNF4G HOMEZ ISY1-RAB43 JRK LDOC1 PPP1CC RSPH14 SMARCD1 SPG21 TCP11X2 TEPSIN TRIM41 YJU2B ZNF438 ZNF835 ZRANB1
Entrez ID		3174	23361
HPRD ID		06909	19016
Ensembl ID		ENSG00000164749	ENSG00000102870
Uniprot IDs		F1D8Q4 Q14541	Q9UEG4
PDB IDs		1LV2
Enriched GO Terms of Interacting Partners?
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