HMOX2 and MGST3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HMOX2	MGST3
Description		heme oxygenase 2	microsomal glutathione S-transferase 3
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Specific Granule Membrane	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Heme Oxygenase (decyclizing) Activity Protein Binding Heme Binding Metal Ion Binding	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Identical Protein Binding
	Biological Process	Response To Hypoxia Heme Oxidation Response To Oxidative Stress Heme Catabolic Process Iron Ion Homeostasis	Lipid Metabolic Process Response To Organonitrogen Compound Leukotriene Biosynthetic Process Cellular Oxidant Detoxification
Pathways		Heme degradation Neutrophil degranulation RHOA GTPase cycle Iron uptake and transport Cytoprotection by HMOX1	Glutathione conjugation Aflatoxin activation and detoxification
Drugs		NADH Stannsoporfin	Glutathione
Diseases
GWAS		Erectile dysfunction ( 30583798)	Metabolite levels ( 23823483) Total ventricular volume ( 21116278)
Interacting Genes		66 interacting genes: A2M APP AQP6 ARL13B ASGR2 ATP5F1B BCL2L13 BLOC1S2 CCR2 CD79A CEBPZ CEP126 COPS6 CRB3 CSNK2A1 EBP EEF1G EIF3C ELOVL4 ERGIC3 F2RL1 FAM209A FAM210B GET1 GIT1 GPR152 GPRASP1 GPX8 HAP1 IMMT INPP5K ITFG1 JADE1 KCNJ6 KCNMA1 LAPTM5 LRIF1 MARK3 MED31 MGST3 MTNR1A NDUFS2 NKRF NR3C1 PLXNB2 PTGER4 RBBP4 RETREG3 RNASEK SAR1A SETDB1 SGPL1 SHC1 SKA2 SLC30A8 SMO SNX5 SNX7 SSMEM1 STOM SYT1 TMEM14B TMX2 VMA21 ZFP28 ZNF746	88 interacting genes: AGPAT4 AGTRAP APOD APOL2 AQP1 AQP10 AQP3 ARL6IP1 ARL6IP6 BET1 BMP10 C11orf24 C14orf180 C3orf52 CACNG1 CCNC CDIPT CLCA4 CLRN1 CMTM5 CREB3L1 CTSA CYBC1 ERG28 F10 FAXDC2 FCGR2A FCGR2B FUNDC2 FXYD6 GIMAP1 GIMAP5 GPR152 GPX8 GRM2 HMOX2 ITGAM LEMD1 LMNA LPAR3 LRP10 MIP MRM1 MTIF3 NEU1 NINJ2 NKG7 NRM NSG1 PAGE1 PLN PLP1 PLP2 PLPP4 SCD SCN3B SEC22B SLC1A3 SLC2A5 SLC35A1 SLC39A9 SLC7A1 SMCO4 SNAP47 SNORC STX3 STX7 STX8 SYS1 TFAM TFRC TMEM107 TMEM109 TMEM120B TMEM140 TMEM229B TMEM60 TMEM86B TMX2 TSPAN12 TSPAN2 TSPAN33 UBIAD1 UNC50 VAMP3 VAMP4 YIF1A ZFPL1
Entrez ID		3163	4259
HPRD ID		00783	05192
Ensembl ID		ENSG00000103415	ENSG00000143198
Uniprot IDs		A0A087WT44 B3KSE0 P30519	A0A024R8Z1 O14880
PDB IDs		2Q32 2QPP 2RGZ 4WMH 5UC8 5UC9 5UCA
Enriched GO Terms of Interacting Partners?
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