HMMR and BACH1

Number of citations of the paper that reports this interaction (PubMedID 26496610)
430

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology)

		HMMR	BACH1
Description		hyaluronan mediated motility receptor	BTB domain and CNC homolog 1
Image		No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol Plasma Membrane Cell Surface Microtubule Cytoskeleton Membrane	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Hyaluronic Acid Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Heme Binding
	Biological Process		Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription Involved In G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II DNA Repair Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Pathways		Hyaluronan uptake and degradation AURKA Activation by TPX2	Regulation of HMOX1 expression and activity Heme signaling Regulation of BACH1 activity
Drugs		Hyaluronic acid
Diseases
GWAS		Metabolite levels ( 23823483)	Alanine aminotransferase levels ( 33547301) Aspartate aminotransferase levels ( 33547301) Creatine kinase levels ( 29403010) Haemorrhoidal disease ( 33888516) Pancreatic cancer ( 22158540) Selective IgA deficiency ( 27723758) Visceral fat ( 22589738)
Interacting Genes		16 interacting genes: ACTB BACH1 CALM1 CD44 CDH13 GREB1 IL24 ITIH5 MAPK3 MORN4 NAT2 SVIL THRSP TPX2 TRIM54 TUBB2A	10 interacting genes: ANAPC5 ATF2 DDIT3 HLCS HMMR MAFB MAFK PATZ1 RBCK1 TCF4
Entrez ID		3161	571
HPRD ID		02963	04127
Ensembl ID		ENSG00000072571	ENSG00000156273
Uniprot IDs		O75330	O14867
PDB IDs			2IHC
Enriched GO Terms of Interacting Partners?
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