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HMGB2 and EIF1
Number of citations of the paper that reports this interaction (PubMedID
29721183
)
4
Data Source:
BioGRID
(two hybrid)
HMGB2
EIF1
Description
high mobility group box 2
eukaryotic translation initiation factor 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Condensed Chromosome
Extracellular Space
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Protein-containing Complex
Perinuclear Region Of Cytoplasm
Nucleus
Cytoplasm
Eukaryotic 43S Preinitiation Complex
Molecular Function
Four-way Junction DNA Binding
Transcription Cis-regulatory Region Binding
Cis-regulatory Region Sequence-specific DNA Binding
DNA Binding
Damaged DNA Binding
Double-stranded DNA Binding
Single-stranded DNA Binding
Transcription Coactivator Activity
RNA Binding
Protein Binding
Transcription Factor Binding
DNA Binding, Bending
Protein Domain Specific Binding
Chemoattractant Activity
Non-sequence-specific DNA Binding, Bending
RAGE Receptor Binding
Supercoiled DNA Binding
RNA Binding
Translation Initiation Factor Activity
Protein Binding
Translation Factor Activity, RNA Binding
Ribosomal Small Subunit Binding
Biological Process
Positive Regulation Of Endothelial Cell Proliferation
Inflammatory Response To Antigenic Stimulus
DNA Topological Change
Double-strand Break Repair Via Nonhomologous End Joining
Chromatin Organization
Nucleosome Assembly
Regulation Of Transcription By RNA Polymerase II
Spermatid Nucleus Differentiation
Male Gonad Development
Negative Regulation Of Gene Expression
Positive Regulation Of Nuclease Activity
DNA Geometric Change
Response To Lipopolysaccharide
Positive Regulation Of Interferon-beta Production
V(D)J Recombination
Positive Regulation Of DNA Binding
Innate Immune Response
Positive Regulation Of Innate Immune Response
Positive Regulation Of Erythrocyte Differentiation
Positive Regulation Of Megakaryocyte Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Response To Steroid Hormone
Regulation Of Neurogenesis
Defense Response To Gram-negative Bacterium
Defense Response To Gram-positive Bacterium
Positive Chemotaxis
Cell Chemotaxis
Cellular Response To Lipopolysaccharide
Regulation Of Stem Cell Proliferation
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Translational Initiation
Regulation Of Translational Initiation
Pathways
Apoptosis induced DNA fragmentation
Drugs
Diseases
GWAS
Interacting Genes
47 interacting genes:
APEX1
APP
AR
ARCN1
C1QBP
CACTIN
CHAF1A
COMMD1
CREBBP
CSNK1A1
EIF1
FBXO7
FLNA
GZMA
GZMK
H3-3A
HACD3
HDLBP
HMGA1
LZTS1
MIEN1
MYL6
NAP1L1
NCBP3
NEXN
NOP53
NR3C1
PGR
PKNOX1
POU2F1
POU2F2
POU3F1
POU5F1
PRKDC
RAG1
RPS28
SAMM50
SET
SNAPIN
TERT
TP53
TSNAX
U2AF1
UHRF2
ZNF428
ZNF622
ZNF668
8 interacting genes:
APP
EIF4G1
HMGB1
HMGB2
MAPK6
OLFM2
RASA1
UPF2
Entrez ID
3148
10209
HPRD ID
01229
15449
Ensembl ID
ENSG00000164104
ENSG00000173812
Uniprot IDs
P26583
P41567
Q6IAV3
PDB IDs
2IF1
4KZX
4KZY
6YBW
6ZMW
6ZP4
6ZVJ
7A09
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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