H1-1 and NASP

Number of citations of the paper that reports this interaction (PubMedID 10893414)
52

Data Source:
HPRD (in vitro, in vivo)

		H1-1	NASP
Description		H1.1 linker histone, cluster member	nuclear autoantigenic sperm protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleosome Euchromatin Nucleus Nucleoplasm	Chromatin Nucleus Nucleoplasm Cytoplasm Protein-containing Complex
	Molecular Function	Double-stranded DNA Binding Protein Binding Chromatin DNA Binding Nucleosomal DNA Binding	Protein Binding Histone Binding
	Biological Process	Nucleosome Assembly Spermatogenesis Nucleosome Positioning Chromosome Condensation Negative Regulation Of DNA Recombination	G1/S Transition Of Mitotic Cell Cycle Blastocyst Development DNA Replication DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Male Gonad Development Protein Transport Response To Testosterone CENP-A Containing Nucleosome Assembly Histone Exchange
Pathways		Apoptosis induced DNA fragmentation Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS			Blood metabolite levels ( 24816252) Blood protein levels ( 28240269) Body mass index ( 26426971) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Hemoglobin levels ( 32327693) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		52 interacting genes: AEBP2 APP CCNA1 CCNA2 CCNB1 CCND2 CCNE1 CDK1 CDK2 CDK4 CDK5 CDK6 CDK7 CDKN1B CRP CTCFL EED EHMT2 EP300 EZH2 GADD45A GZMA IRAK4 KAT2B LIMK1 LIMK2 LOX NAP1L1 NAP1L4 NASP NSD3 PAK4 PARP1 PARP3 PELP1 PRDM1 PRKCA PRKCB PRKCD PRKCE PRKCZ PRKDC PTMA RBBP4 RPS6KA5 SET SNCA SUZ12 TAF1 TERF1 TERF2IP TLK1	27 interacting genes: CDC42 FXR2 H1-1 H1-2 H3-4 H3-5 H3C10 H3C11 H3C12 H3C13 H3C14 H3C15 H3C2 H3C3 H3C4 H3C6 H3C7 H3C8 HDAC6 LUC7L2 MTNR1A OGT PTK2 ST3GAL3 TERF2 TERF2IP ULK2
Entrez ID		3024	4678
HPRD ID		00820	04423
Ensembl ID		ENSG00000124610	ENSG00000132780
Uniprot IDs		Q02539	P49321 Q5T626
PDB IDs
Enriched GO Terms of Interacting Partners?
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