SLC2A8 and BDKRB2

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		SLC2A8	BDKRB2
Description		solute carrier family 2 member 8	bradykinin receptor B2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Clathrin-coated Endocytic Vesicle Membrane	Endosome Golgi Apparatus Plasma Membrane Integral Component Of Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Fructose Transmembrane Transporter Activity Glucose Transmembrane Transporter Activity Glucose Binding Dehydroascorbic Acid Transmembrane Transporter Activity D-glucose Transmembrane Transporter Activity	Protease Binding Phosphatidylinositol Phospholipase C Activity G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Type 1 Angiotensin Receptor Binding Protein Heterodimerization Activity
	Biological Process	Response To Hypoxia Carbohydrate Metabolic Process Male Meiosis I Insulin Receptor Signaling Pathway Hexose Transmembrane Transport Fructose Transmembrane Transport Dehydroascorbic Acid Transport Glucose Transmembrane Transport	Smooth Muscle Contraction Inflammatory Response Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Blood Circulation Response To Salt Stress Regulation Of Vasoconstriction Negative Regulation Of Peptidyl-serine Phosphorylation Vasoconstriction Vasodilation Regulation Of Vascular Permeability Arachidonic Acid Secretion Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress By P53 Class Mediator
Pathways		Cellular hexose transport Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
Drugs			Anatibant Icatibant Labradimil
Diseases
GWAS		Bipolar disorder ( 20351715) Major depressive disorder ( 27777418) Metabolite levels (HVA) ( 23319000)	Cerebrospinal fluid AB1-42 levels ( 28247064) Corneal astigmatism ( 30306274) Gout ( 22179738) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Gut microbiota relative abundance (unclassified genus belonging to the order Clostridiales) ( 33208821) Mumps ( 28928442) Subcutaneous adipose tissue ( 26480920)
Interacting Genes		4 interacting genes: AP1B1 AP2A2 AP2B1 BDKRB2	33 interacting genes: AATK ACE AGTR1 AP2M1 CD81 CD82 CLCA4 EFS GNA11 GRK2 GRK3 GRK4 GRK5 GRK6 HERC2 INF2 MPI NIF3L1 NOS1 NOS3 PEX16 PRKCD PTPN11 SLC2A8 SLC35A4 SPG7 SPNS1 SYNE1 SYNGR2 TMEM11 TMEM70 TPI1 USP4
Entrez ID		29988	624
HPRD ID		05580	00213
Ensembl ID		ENSG00000136856	ENSG00000168398
Uniprot IDs		A0A024R871 A0A087WT42 Q5VVV9 Q8WZ05 Q9NY64	P30411
PDB IDs
Enriched GO Terms of Interacting Partners?
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