PSAT1 and CEBPE

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		PSAT1	CEBPE
Description		phosphoserine aminotransferase 1	CCAAT enhancer binding protein epsilon
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome	Chromatin Nucleus
	Molecular Function	O-phospho-L-serine:2-oxoglutarate Aminotransferase Activity Protein Binding Pyridoxal Phosphate Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Protein-containing Complex Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	L-serine Biosynthetic Process Pyridoxine Biosynthetic Process	Regulation Of Transcription By RNA Polymerase II Phagocytosis Defense Response Positive Regulation Of Gene Expression Myeloid Cell Differentiation Macrophage Differentiation Granulocyte Differentiation Defense Response To Bacterium Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Lipopolysaccharide
Pathways		Serine biosynthesis	Transcriptional regulation of granulopoiesis
Drugs		Pyridoxal phosphate Glutamic acid
Diseases
GWAS		Daytime nap ( 33568662) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Visceral fat ( 22589738)	Acute lymphoblastic leukemia (B-cell precursor) ( 23996088) Acute lymphoblastic leukemia (childhood) ( 29348612 22076464 23512250 19684604) Acute lymphoblastic leukemia in childhood (B cell precursor) ( 29632299) B-cell acute lymphoblastic leukaemia ( 31767839) Basophil count ( 32888494) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 32888494 27863252) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Monocyte count ( 29403010 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Sum eosinophil basophil counts ( 27863252) White blood cell count (basophil) ( 29403010 27863252 28158719)
Interacting Genes		6 interacting genes: APP CDC42 CEBPE DOCK1 MAPK6 PSMD10	45 interacting genes: ALX4 ATF3 ATF4 ATF5 BATF BATF2 BATF3 CCT7 CEBPA CEBPD CEBPG COPS3 CSNK1A1L DDIT3 DENND4A E2F1 EDA2R ELOB FOS FOSL1 GATA1 GPR22 GTF2A1L IL7 JUN KDM2B LDOC1 MED16 MLLT6 MYB NELFB PIAS1 POU2F1 PSAT1 RB1 SIPA1L1 SPI1 STAT6 TAF5L TBX2 TRIB1 UBE2I ZFP2 ZMYM2 ZNF384
Entrez ID		29968	1053
HPRD ID		17918	02852
Ensembl ID		ENSG00000135069	ENSG00000092067
Uniprot IDs		A0A024R222 A0A024R280 Q9Y617	Q15744
PDB IDs		3E77	3T92
Enriched GO Terms of Interacting Partners?
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