GTF2H1 and REEP5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		GTF2H1	REEP5
Description		general transcription factor IIH subunit 1	receptor accessory protein 5
Image			No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIH Core Complex Nucleoplasm Transcription Factor TFIIH Holo Complex	Endoplasmic Reticulum Integral Component Of Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	Chromatin Binding Protein Binding Thyroid Hormone Receptor Binding	Molecular_function Protein Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity DNA Repair Nucleotide-excision Repair Transcription By RNA Polymerase I Transcription By RNA Polymerase II Hormone-mediated Signaling Pathway Positive Regulation Of Transcription, DNA-templated Phosphorylation Of RNA Polymerase II C-terminal Domain	Endoplasmic Reticulum Organization Biological_process Regulation Of Intracellular Transport
Pathways		Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex RNA Pol II CTD phosphorylation and interaction with CE during HIV infection HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome Formation of HIV-1 elongation complex containing HIV-1 Tat Tat-mediated elongation of the HIV-1 transcript NoRC negatively regulates rRNA expression Formation of Incision Complex in GG-NER Dual Incision in GG-NER RNA Polymerase II Pre-transcription Events Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER TP53 Regulates Transcription of DNA Repair Genes mRNA Capping RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase I Transcription Termination RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Elongation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Pol II CTD phosphorylation and interaction with CE	Olfactory Signaling Pathway
Drugs
Diseases
GWAS		Amyloid A serum levels ( 21124955) Blood protein levels ( 28240269) Pancreatic cancer ( 23180869) Serum metabolite levels ( 33031748 23093944) Survival in pancreatic cancer ( 28470677) Systemic lupus erythematosus ( 33272962)	Attention deficit hyperactivity disorder ( 18839057) Daytime nap ( 33568662) Reaction time ( 29844566)
Interacting Genes		46 interacting genes: ACTN1 AGTRAP AR ATF7IP BRPF1 CCNH CCSER2 CDK7 E2F1 EAF1 ERCC2 ERCC3 ERCC4 ERCC5 ESR1 FHL2 FUBP1 GTF2E1 GTF2E2 GTF2H2 HNF4A HNRNPU HOXC11 JDP2 KIF13A KPNA3 MCM2 MMS19 MNAT1 OGT PIK3R1 PLCG1 POU2AF1 PSMC2 RAD23A REEP5 RXRB TNIP1 TP53 TRIOBP TXNRD2 UBC USHBP1 XPA XPC ZSCAN1	22 interacting genes: ABHD4 ARFGAP1 ARFIP2 CD14 CHRM5 CPOX EDC3 GPX3 GTF2H1 HBEGF LGR5 NUDT3 PBX3 PDK4 PDLIM3 PITPNC1 RAB5B RABAC1 RGS2 SNX1 TENT4A VKORC1
Entrez ID		2965	7905
HPRD ID		01807	15918
Ensembl ID		ENSG00000110768	ENSG00000129625
Uniprot IDs		A0A384MTQ8 P32780	Q00765
PDB IDs		1PFJ 2DII 2RNR 2RUK 2RVB 5GOW 5XV8 6NMI 6O9L 6O9M 7BUL
Enriched GO Terms of Interacting Partners?
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