GTF2E1 and TBC1D21

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GTF2E1	TBC1D21
Description		general transcription factor IIE subunit 1	TBC1 domain family member 21
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIE Complex Cytosol Transcription Preinitiation Complex	Acrosomal Vesicle Cytoskeleton Extracellular Exosome
	Molecular Function	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Metal Ion Binding	Actin Binding GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	Transcription Open Complex Formation At RNA Polymerase II Promoter Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter	Intracellular Protein Transport Spermatogenesis Cell Differentiation Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Coffee consumption (cups per day) ( 31837886) Estimated glomerular filtration rate ( 31152163) Exfoliation glaucoma or exfoliation syndrome ( 24938310) Feeling fed-up ( 29500382) Glucose homeostasis traits ( 25524916) LDL cholesterol levels in HIV infection ( 33109212)
Interacting Genes		36 interacting genes: APP CBFA2T2 CDK7 EPHB1 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 IKBKG NRARP OGT PCBD2 POLR2A SND1 SRPK2 TAF1 TAF11 TAF6 TBC1D21 TBP TCEA1 TLE5 TRIM15 TRIM24 TRIM29 ZBTB9 ZSCAN1	29 interacting genes: APP CCDC158 CFAP53 EVI5L GAS2 GFAP GTF2E1 KIF26A KRT15 KRT35 KRT37 KRT38 KRT40 LCN2 MEOX2 NR1D2 NUTM1 PDCD2 PMF1 PMF1-BGLAP RAB3IP REL RIBC1 SAMD4A SEPTIN2 SNX7 STMN3 TCF12 TIMM10
Entrez ID		2960	161514
HPRD ID		01799	15473
Ensembl ID		ENSG00000153767	ENSG00000167139
Uniprot IDs		P29083	Q8IYX1
PDB IDs		1VD4 2JTX 2RNQ 2RNR 5GPY 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6O9L
Enriched GO Terms of Interacting Partners?
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