CTNNA3 and PCF11

		CTNNA3	PCF11
Description		catenin alpha 3	PCF11 cleavage and polyadenylation factor subunit
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Adherens Junction Fascia Adherens Lamellipodium	Nucleoplasm Cytoplasm Mitochondrion MRNA Cleavage Factor Complex
	Molecular Function	Protein Binding Beta-catenin Binding Cadherin Binding Actin Filament Binding	RNA Polymerase II Complex Binding MRNA Binding
	Biological Process	Actin Filament Organization Cell Migration Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Regulation Of Heart Rate By Cardiac Conduction Epithelial Cell-cell Adhesion Cell-cell Adhesion Regulation Of Ventricular Cardiac Muscle Cell Action Potential	Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Cleavage
Pathways			RNA polymerase II transcribes snRNA genes mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Adverse response to drug ( 30420678) Asthma (toluene diisocyanate-induced) ( 19187332) Bronchopulmonary dysplasia ( 23897914) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Dental caries ( 23064961) Diffusing capacity of carbon monoxide ( 30694715) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Essential tremor ( 27797806) General risk tolerance (MTAG) ( 30643258) Household income (MTAG) ( 31844048) Lung function (FVC) ( 24023788) Metabolite levels ( 23823483) Metabolite levels (Pyroglutamine) ( 23934736) Mitochondrial DNA copy number ( 30704525) Nickel levels ( 26025379) Nicotine dependence ( 17158188) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Optic disc area ( 28073927) Psoriatic arthritis ( 26626624) Pulse pressure ( 27841878) Rheumatic heart disease ( 34106200) Schizophrenia (cytomegalovirus infection interaction) ( 23358160) Subcutaneous adipose tissue ( 29178545) Systemic lupus erythematosus ( 28714469) Systolic blood pressure ( 27841878)	Age-related macular degeneration ( 23326517) Obesity-related traits ( 23251661)
Interacting Genes		71 interacting genes: AKAP9 ATP23 BLOC1S2 BLZF1 C17orf50 CCDC183 CCDC33 CDSN CENPS-CORT CKMT1A CKMT1B CMC2 COG4 CRX CTNNB1 DISC1 DNAJC9 ECSIT EID2B EPS8 FAM110A FAM161A FAM161B FAM9A FBXO28 FERD3L GINS3 GNB1 HDX HOMEZ JUP KATNAL1 LASP1 MARCHF7 MBD3L1 MSRA MYOG NAB2 NDUFB7 OIP5 ORC2 PAX6 PCF11 PLAGL2 PNMA1 PNMA5 POU6F2 PPARA PPP2R5E PRR5 REL RIPPLY1 RPS6KA5 SERTAD2 SPATS1 STMN2 TASOR2 TLX3 TNNI1 TNNI2 TRIM54 TXNRD3 USHBP1 VIP ZG16 ZNF19 ZNF426 ZNF474 ZNF552 ZNF620 ZNF662	3 interacting genes: CTNNA3 MAGEA11 SRPK2
Entrez ID		29119	51585
HPRD ID		09639	10592
Ensembl ID		ENSG00000183230	ENSG00000165494
Uniprot IDs		A8K141 Q8WW10 Q9UI47	O94913
PDB IDs			6WJH
Enriched GO Terms of Interacting Partners?
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