MACROD1 and UXT

Number of citations of the paper that reports this interaction (PubMedID 21483817)
22

Data Source:
BioGRID (pull down)

		MACROD1	UXT
Description		mono-ADP ribosylhydrolase 1	ubiquitously expressed prefoldin like chaperone
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Chromatin Spindle Pole Nucleus Nucleoplasm Cytoplasm Centrosome Cytoskeleton
	Molecular Function	Protein Binding Hydrolase Activity, Acting On Glycosyl Bonds Deacetylase Activity ADP-ribosylglutamate Hydrolase Activity	Chromatin Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Purine Nucleoside Metabolic Process Protein De-ADP-ribosylation Peptidyl-glutamate ADP-deribosylation	Negative Regulation Of Transcription By RNA Polymerase II Microtubule Cytoskeleton Organization Regulation Of Transcription By RNA Polymerase II Apoptotic Process Centrosome Cycle Mitochondrion Transport Along Microtubule
Pathways			Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Body mass index ( 25673413) Body mass index and HDL-C (pairwise) ( 33619380) Body mass index and triglycerides (pairwise) ( 33619380) Body shape index ( 34021172) Fasting insulin ( 34059833) Fruit consumption ( 32066663) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) High density lipoprotein cholesterol levels ( 33339817) Hip circumference adjusted for BMI ( 34021172 25673412) Hip index ( 34021172) Immature fraction of reticulocytes ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Serum uric acid levels ( 32514006) Triacylglycerol 56:6 levels ( 31560688) Triglyceride levels ( 33339817) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Urate levels ( 31578528) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		4 interacting genes: EPB41 IKBKG KPNA1 UXT	29 interacting genes: APP AR CECR2 DYNLT1 GLE1 KRT31 KRT40 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP5-7 KRTAP5-9 LRPPRC LSM1 MACROD1 MCPH1 MPP1 NBPF19 NOTCH2NLA PAK5 RCAN1 RUNX1 SIAH1 SVIL TRIM55 TRIM63 TXNIP VHL
Entrez ID		28992	8409
HPRD ID		17448	02209
Ensembl ID		ENSG00000133315	ENSG00000126756
Uniprot IDs		A0A6Q8PH91 Q9BQ69	Q9UBK9
PDB IDs		2X47 6LH4
Enriched GO Terms of Interacting Partners?
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