GPS2 and RBPMS

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		GPS2	RBPMS
Description		G protein pathway suppressor 2	RNA binding protein, mRNA processing factor
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Mitochondrion Cytosol Transcription Repressor Complex	P-body Nucleoplasm Cytosol Cytoplasmic Stress Granule
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity GTPase Inhibitor Activity Protein Binding Cyclin Binding	Transcription Coactivator Activity RNA Binding MRNA Binding Protein Binding Poly(A) Binding Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II JNK Cascade Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Cholesterol Efflux Regulation Of Lipid Metabolic Process B Cell Differentiation Negative Regulation Of Toll-like Receptor Signaling Pathway Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Negative Regulation Of Catalytic Activity Regulation Of Fat Cell Differentiation Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of JNK Cascade Negative Regulation Of Inflammatory Response Negative Regulation Of B Cell Receptor Signaling Pathway Response To Mitochondrial Depolarisation Negative Regulation Of Protein K63-linked Ubiquitination	RNA Processing Response To Oxidative Stress Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of SMAD Protein Signal Transduction
Pathways		PPARA activates gene expression HDACs deacetylate histones Loss of MECP2 binding ability to the NCoR/SMRT complex Regulation of MECP2 expression and activity NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux HCMV Early Events
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514)	Blood urea nitrogen levels ( 31152163) Breast size ( 27182965) Eosinophil counts ( 32888494) Granulocyte count ( 27863252) Heart rate variability traits ( 22174390) Lymphocyte percentage of white cells ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494 27863252 28017375) Mean corpuscular volume ( 29403010 32888494 27863252 28017375) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Neutrophil percentage of white cells ( 32888494) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) PR interval ( 32439900) Serum alkaline phosphatase levels ( 33547301) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systolic blood pressure ( 30224653) Total grey matter volume ( 31530798) White blood cell count ( 32888494)
Interacting Genes		55 interacting genes: AKAP8L ATF4 ATF5 BAG4 BRME1 C19orf54 CCNA1 CHD3 CNOT2 CYSRT1 DAZAP2 ELOB EP300 FAM168B FHL5 GOLGA2 HDAC1 HDAC3 HNRNPH1 HOXA1 INTS11 KRT27 KRT31 KRT34 KRT36 KRTAP11-1 KRTAP13-2 KRTAP3-1 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 MAP3K7CL MYH10 NCOR1 NDOR1 NR0B2 OIP5 PBK POU2AF1 PRMT6 PRR22 RBPMS SESTD1 SETDB1 SMUG1 SPDL1 TBL1X TBL1XR1 TFIP11 TP53 TP53BP2 TRIP6 UBTD2 VPS37C	265 interacting genes: ABCF3 ADAM15 AMMECR1 ANAPC11 ANKMY1 APLN ARHGAP9 ARHGEF39 ARID5A ATN1 ATP6V0D1 ATP6V0E2 ATXN1 ATXN7L2 BANP BBS2 BCL6B BHLHE40 BOLL C10orf55 C11orf87 C19orf54 C1orf94 C20orf85 C22orf39 C9orf24 CAMK2A CAMK2B CCDC120 CCER1 CCNG1 CCNK CDC23 CDC42EP1 CDK6 CHCHD7 CLPP CNNM3 COL8A1 CRBN CREB5 CRX CRYBA1 CSN3 CSNK1G2-AS1 CYBA DAZAP2 DCAF8 DCDC2B DCTN5 DMRT3 DMRTB1 DOK3 DOK6 DPYSL4 DTX2 DVL2 EAF2 EFEMP2 ENKD1 EWSR1 EXOSC1 EYA2 FAM124B FAM166B FAM168A FASTK FBF1 FBXL18 FNDC11 FOXC2 FOXP3 FOXS1 FRG1 FXR2 GATA1 GATA2 GATAD2B GCM2 GLIS2 GLYCTK GPATCH2L GPS2 GRAP GRAP2 GSE1 GTF2F2 HCK HEY2 HEYL HIVEP1 HNRNPLL HOXA1 HOXA9 HOXB9 HOXC8 HSFY1 IDO1 IGF2 ILF3 INCA1 INIP IP6K2 KCTD9 KIF1A KIR2DL4 KLHDC7B KPNA2 KRAS KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-4 KRTAP13-1 KRTAP13-3 KRTAP15-1 KRTAP19-1 KRTAP19-3 KRTAP19-5 KRTAP19-7 KRTAP23-1 KRTAP26-1 KRTAP3-1 KRTAP8-1 LASP1 LGALS9C LINC00482 LINC00588 LINC00908 LINC01547 LINC01588 LINC01869 LMO4 LONRF1 LRRC41 LZTS2 MAGED1 MCM5 MCM7 MEIS2 MGAT5B MKRN3 MLLT10 MORN3 MRPL20-AS1 MSX1 MVP MYH7B MYOZ2 NAB2 NANOG NAPRT NEDD9 NEU4 NKX2-5 NR1D2 NTAQ1 NYNRIN OTX1 PATZ1 PDLIM4 PER1 PGLS PHF1 PICALM PIH1D1 PIN1 PITX1 PITX2 PLAC8 PLSCR4 POGZ POLR3GL POM121 POU4F2 POU6F2 PPP1R16B PRKAA1 PRKAA2 PRKAB2 PRR20A PRR20B PRR20C PRR20D PRR20E PRR35 PSG11 PSMF1 QKI R3HDM2 RABL6 RAD54L2 RAMAC RBFOX1 RBFOX2 RBM24 RBM46 RBPMS2 RDH12 RHOBTB3 RHOXF2 RIPPLY1 ROR2 RPP25 RTP5 RUSC1 SBF2 SEMA4G SERF2 SF1 SFI1 SH3RF2 SIRPB1 SLC25A48 SMAD3 SMAP1 SMUG1 SNHG29 SNRPB SNRPC SPATA46 SPATA8 SPG7 STRBP TBX6 TCEA2 TCF7L2 TEKT5 TENT2 TEX37 TFG TIE1 TINAGL1 TLE5 TMEM42 TMSB4X TNS2 TOLLIP TOR1AIP2 TRAF4 TRIP13 TSC1 TSG101 TSGA10IP TSPYL6 TTLL10 TUSC2 UBAP2 UBXN8 VENTX VEZF1 VGLL3 VHL VHLL VPS37C WDR54 WDR90 YPEL3 ZBTB32 ZC3H10 ZIC1 ZNF34 ZNF385C ZNF488 ZNF581
Entrez ID		2874	11030
HPRD ID		11878	11870
Ensembl ID		ENSG00000132522	ENSG00000157110
Uniprot IDs		Q13227	B4E3T4 D3DSV0 Q93062
PDB IDs		2L5G	1BNY 5CYJ 5DET
Enriched GO Terms of Interacting Partners?
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