FFAR2 and TMEM239

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FFAR2	TMEM239
Description		free fatty acid receptor 2	transmembrane protein 239
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Projection	Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Lipid Binding	Protein Binding
	Biological Process	Leukocyte Chemotaxis Involved In Inflammatory Response Mucosal Immune Response Regulation Of Acute Inflammatory Response Positive Regulation Of Cytokine Production Involved In Immune Response Cell Surface Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus G Protein-coupled Receptor Signaling Pathway Lipid Storage Positive Regulation Of Chemokine Production Positive Regulation Of Interleukin-8 Production Glucose Homeostasis Fat Cell Differentiation Cellular Response To Fatty Acid Regulation Of Peptide Hormone Secretion
Pathways		G alpha (q) signalling events Free fatty acid receptors
Drugs
Diseases
GWAS		Hemoglobin ( 32888494) Iron status biomarkers (iron levels) ( 33536631) Iron status biomarkers (transferrin saturation) ( 33536631) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494)	Estimated glomerular filtration rate ( 31451708) Pulse pressure ( 30224653) White matter integrity ( 23218918)
Interacting Genes		110 interacting genes: AGPAT4 AGTRAP ALOX5AP APOD ATP13A1 ATP6V0C BMP10 BNIP3 BTN2A2 C11orf24 C3orf52 C4orf3 CACNG1 CBLIF CCDC167 CD82 CDIPT CFHR5 CGRRF1 CLDN4 CLDND2 CLEC1A CMTM5 CMTM7 CNIH1 COL4A5 CXCL16 CXCL9 CYB561A3 CYB5R2 DERL1 EDDM3B EMP1 ERG28 FAM20B FAM3C FAXDC2 FCER1G FIS1 FXYD3 FXYD6 FZD7 GALNT15 GJB2 GNAO1 GNAQ GPR37L1 GUCA2A GYPA IFITM3 IGF1R KRT1 KTN1 LAPTM4A LAT LEPROTL1 LHFPL5 LPAR3 MALL MFSD5 MS4A13 NAT8 NIPAL4 NKG7 NRM NSG1 NUCB2 OR10AG1 PEX16 PLP1 PMP22 PNLIPRP1 RPRM RTP2 RUSF1 SACM1L SCGB1D1 SELENOK SLC30A2 SLC35B4 SLC35C2 SLC35E3 SLC38A1 SLC39A9 SLC41A1 SMAGP SMCO4 SMIM1 STRIT1 STX8 SYNDIG1 TEX264 TM4SF4 TMEM11 TMEM120B TMEM144 TMEM147 TMEM203 TMEM239 TMEM262 TMEM60 TMEM86A TMEM97 TNF TSPO2 UNC50 UPK1B YIF1A YIPF2 YIPF6	67 interacting genes: AQP6 ATF7 CD79A CLDN20 CLRN1 COQ8A CREB3L1 CREB3L3 CXCL16 DARS2 DCUN1D1 EBP EMP1 FAM174A FBXL19 FFAR2 FGD2 FKBP7 FTHL17 FXYD6 GJA8 GPR101 GPR151 GPR42 LENG1 LNX1 MFSD14B MIEF2 MPP1 MS4A3 MTIF3 MTURN MYG1 NTAQ1 OCIAD1 ODF4 OTULIN PDCD1LG2 PNKP POLI PSCA REEP2 RETREG3 S100B SCAND1 SCN3B SDCBP SENP2 SERINC2 SLC10A1 SLC10A6 SLC18A1 SLC34A2 SLC35C2 SNX1 SNX2 SPG21 SSMEM1 SYT16 TBRG4 TIMMDC1 TMEM248 TMEM31 TMX2 TRHR UBASH3A USP5
Entrez ID		2867	100288797
HPRD ID		04824
Ensembl ID		ENSG00000126262	ENSG00000198326
Uniprot IDs		C6KYL4 O15552	Q8WW34
PDB IDs
Enriched GO Terms of Interacting Partners?
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