SREK1IP1 and HPRT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SREK1IP1	HPRT1
Description		SREK1 interacting protein 1	hypoxanthine phosphoribosyltransferase 1
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Nucleic Acid Binding Protein Binding Zinc Ion Binding	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Binding Identical Protein Binding Guanine Phosphoribosyltransferase Activity
	Biological Process	MRNA Processing RNA Splicing	T Cell Mediated Cytotoxicity Response To Amphetamine Purine Nucleotide Biosynthetic Process Purine Ribonucleoside Salvage Adenine Salvage Guanine Salvage Grooming Behavior Locomotory Behavior Striatum Development Cerebral Cortex Neuron Differentiation Central Nervous System Neuron Development GMP Salvage IMP Salvage Dopamine Metabolic Process Hypoxanthine Salvage AMP Salvage Positive Regulation Of Dopamine Metabolic Process GMP Catabolic Process IMP Metabolic Process Hypoxanthine Metabolic Process Lymphocyte Proliferation Dendrite Morphogenesis Protein Homotetramerization
Pathways			Purine salvage
Drugs			Mercaptopurine 5-O-phosphono-alpha-D-ribofuranosyl diphosphate 5-monophosphate-9-beta-D-ribofuranosyl xanthine 3H-pyrazolo[4,3-d]pyrimidin-7-ol 9-Deazaguanine
Diseases
GWAS		General cognitive ability ( 29844566)	Estimated glomerular filtration rate ( 31015462)
Interacting Genes		28 interacting genes: AGPAT3 C4orf45 CCNL1 CT45A1 DDIT4L ELOA2 FGF10 GTF2H4 H2BC15 HPRT1 HSD17B14 LYAR MACROH2A1 NKAPD1 NKAPL NME1 PPCDC PRPF40A PRR13 RBM39 RNF151 RP9 RP9P RPL9 SDCBP SDCBP2 STAC3 THAP1	12 interacting genes: EEF2KMT EFCAB3 FANCA FXR1 GNMT ISCU NTAQ1 PCNT PRTFDC1 SDCBP SPG21 SREK1IP1
Entrez ID		285672	3251
HPRD ID		08210	02388
Ensembl ID		ENSG00000153006	ENSG00000165704
Uniprot IDs		Q8N9Q2	A0A140VJL3 P00492
PDB IDs			1BZY 1D6N 1HMP 1Z7G 2VFA 3GEP 3GGC 3GGJ 4IJQ 4KN6 4RAB 4RAC 4RAD 4RAN 4RAO 4RAQ 5BRN 5BSK 5HIA 5W8V 6BNJ
Enriched GO Terms of Interacting Partners?
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