GPR25 and SLC16A7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GPR25	SLC16A7
Description		G protein-coupled receptor 25	solute carrier family 16 member 7
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding	Pyruvate Secondary Active Transmembrane Transporter Activity Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Lactate Transmembrane Transporter Activity Symporter Activity Pyruvate Transmembrane Transporter Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway	Monocarboxylic Acid Transport Lactate Transmembrane Transport Transport Across Blood-brain Barrier Pyruvate Transmembrane Transport
Pathways		G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production	Proton-coupled monocarboxylate transport
Drugs			Pyruvic acid
Diseases
GWAS		Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Refractive error ( 32231278)	Adventurousness ( 30643258) Calcium levels ( 25972035) General risk tolerance (MTAG) ( 30643258) Hematocrit ( 29403010) Kawasaki disease ( 33692975) Logical memory (delayed recall) in normal cognition ( 29274321) Logical memory (immediate recall) in normal cognition ( 29274321) Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901) Takayasu arteritis ( 25604533)
Interacting Genes		32 interacting genes: AQP6 ATP6V0C ATP6V0E1 BEST2 CNIH4 CREB3L1 CREB3L3 FATE1 GGT7 GJB1 IKBIP KASH5 LDLRAD1 LMNA MAP3K7 MFSD5 MMGT1 NAALADL2 PNMA1 RETN RHCG SHISAL1 SLC16A7 SLC35E3 SLCO4A1 STOM TMEM237 TMEM248 TMEM52B TPRA1 TSPAN12 VAPB	15 interacting genes: ACSL5 CDIPT COMT CPEB1 FXYD6 GPR25 HMOX1 IFITM3 LEMD1 SFXN1 SMAGP SNTA1 TIMM23 VAPA VTI1B
Entrez ID		2848	9194
HPRD ID		03707	06791
Ensembl ID		ENSG00000170128	ENSG00000118596
Uniprot IDs		O00155	A0A024RBB2 O60669
PDB IDs			7BP3
Enriched GO Terms of Interacting Partners?
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