KANSL1 and MAGEA12

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		KANSL1	MAGEA12
Description		KAT8 regulatory NSL complex subunit 1	MAGE family member A12
Image			No pdb structure
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Kinetochore Nucleus Nucleoplasm NSL Complex MLL1 Complex	Cellular_component Nucleus
	Molecular Function	Protein Binding Histone Acetyltransferase Binding	Molecular_function Protein Binding Histone Deacetylase Binding
	Biological Process	Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation	Negative Regulation Of Transcription By RNA Polymerase II Biological_process
Pathways		HATs acetylate histones
Drugs
Diseases
GWAS		Alcohol use disorder (total score) ( 30336701) Alzheimer's disease in APOE e4- carriers ( 25778476) Automobile speeding propensity ( 30643258) Body shape index ( 34021172) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 29059683) Chronotype ( 30696823) Cognitive ability ( 29186694) Cognitive function ( 28093568) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) General factor of neuroticism ( 30867560) Hand grip strength ( 29313844) Handedness (Left-handed vs. non-left-handed) ( 30980028) Handedness (Right-handed vs. non-right-handed) ( 30980028) Hemoglobin levels ( 32327693) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Household income ( 31844048) Idiopathic pulmonary fibrosis ( 24429156) Leftâ€“right brain asymmetry ( 33723403) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lung function (FEV1) ( 28166213) Lung function (FVC) ( 28166213) Lung function (low FEV1 vs high FEV1) ( 26423011) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Lymphocyte percentage of white cells ( 27863252) Macular thickness ( 30535121) Male-pattern baldness ( 27182965 28196072) Mean corpuscular hemoglobin ( 29403010 32888494 27863252) Mean corpuscular volume ( 29403010 27863252) Mean reticulocyte volume ( 32888494) Monocyte percentage of white cells ( 32888494) Neuroticism ( 29255261) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 32888494 27863252) Oily fish consumption ( 32066663) Osteoarthrosis (time to event) ( 32589924) Parkinson's disease ( 32201043 31660654 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Plateletcrit ( 32888494) Pork consumption ( 32066663) Pulse pressure ( 27841878) Reaction time ( 29844566) Red blood cell count ( 29403010) Red cell distribution width ( 32888494 28957414) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Risk-taking tendency (4-domain principal component model) ( 30643258) Sum eosinophil basophil counts ( 27863252) Systolic blood pressure ( 27841878) Ventral diencephalon volume ( 31530798) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White matter integrity (mean diffusivity) ( 32358547)
Interacting Genes		34 interacting genes: BAZ1B CALCOCO2 CCDC136 CCDC85B CDC5L CDR2 CEP70 DISC1 DTNBP1 EXOC1 FSD2 GOLGA2 HOOK2 HSPB1 KDM1A KIFC3 KRT15 MAGEA12 MDFI NECAB2 NINL NUP62 NUTM1 PLEKHA5 PNMA1 PSME3 RETREG3 SMAD3 SPAG5 TFIP11 TRAF2 TRAF4 TRIM27 USHBP1	22 interacting genes: ABI3 C16orf87 CLIP4 FASTKD3 FNDC11 HELT HK2 KANSL1 KHDC4 MTFR1L MTFR2 NANOS2 NPPA NTAQ1 POLL POU6F2 SCMH1 STAT5A TBC1D19 TCP11L1 UBE3A ZNF33B
Entrez ID		284058	4111
HPRD ID		11254	02169
Ensembl ID		ENSG00000120071	ENSG00000213401
Uniprot IDs		A0A024R9Y2 A0A1W2PRB5 Q7Z3B3	P43365
PDB IDs		4CY1 4CY2
Enriched GO Terms of Interacting Partners?
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