CCDC88B and LMNB2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CCDC88B	LMNB2
Description		coiled-coil domain containing 88B	lamin B2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Centrosome Membrane	Nuclear Inner Membrane Intermediate Filament Nuclear Membrane
	Molecular Function	Protein Binding Microtubule Binding Dynein Light Intermediate Chain Binding	Molecular_function Protein Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Cytokine Production Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Positive Regulation Of T Cell Proliferation Defense Response To Protozoan Positive Regulation Of T Cell Activation	Biological_process
Pathways
Drugs
Diseases
GWAS		Basal cell carcinoma ( 31174203 33549134) Crohn's disease ( 28067908) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Inflammatory bowel disease ( 23128233) Keratinocyte cancer (MTAG) ( 31174203) Leprosy ( 25642632) Medication use (thyroid preparations) ( 31015401) Primary biliary cholangitis ( 26394269) Primary sclerosing cholangitis ( 27992413) Sarcoidosis ( 22837380) Triglyceride levels ( 32154731) Type 1 diabetes ( 34127860) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		41 interacting genes: BEX2 C1orf109 CARD9 CCHCR1 CDK18 CWF19L2 DEF6 DTNB EXOSC5 FAM161A FAM161B GEM HCK HOXB5 JAKMIP2 KANK2 LMNB1 LMNB2 LMO1 LNX1 NME7 PBX2 PIN1 PLEKHA5 PPP1R18 RALBP1 RBM7 RINT1 SH2D4A SH3KBP1 SRPK2 TBC1D22B TRAF3IP3 TSC1 TSG101 TSGA10 TSGA10IP TSHZ2 TXLNB USP2 ZC2HC1C	28 interacting genes: AMOT AMOTL2 CA8 CCDC120 CCDC88B CDC37 EFHC2 FH GOLGA2 LZTS1 MFAP1 MID2 OVOL1 PIBF1 POU6F2 PPP1R13B PRKCD SVIL TFIP11 THAP1 TMPO TP53BP2 TRIM27 TSGA10IP USP2 WASHC3 ZC2HC1C ZFHX3
Entrez ID		283234	84823
HPRD ID		10986	01037
Ensembl ID		ENSG00000168071	ENSG00000176619
Uniprot IDs		A6NC98 B2RTU8	Q03252
PDB IDs			2LLL 5BNW
Enriched GO Terms of Interacting Partners?
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