DESI1 and SLC25A17

		DESI1	SLC25A17
Description		desumoylating isopeptidase 1	solute carrier family 25 member 17
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Protein-containing Complex	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Cytosol Membrane
	Molecular Function	Protein Binding Identical Protein Binding Importin-alpha Family Protein Binding SUMO-specific Isopeptidase Activity	Adenine Nucleotide Transmembrane Transporter Activity ATP Transmembrane Transporter Activity Protein Binding ADP Transmembrane Transporter Activity Coenzyme A Transmembrane Transporter Activity FAD Transmembrane Transporter Activity FMN Transmembrane Transporter Activity Chaperone Binding NAD Transmembrane Transporter Activity AMP Transmembrane Transporter Activity
	Biological Process	Protein Export From Nucleus Protein Desumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Modification By Small Protein Removal	Fatty Acid Alpha-oxidation Fatty Acid Beta-oxidation ADP Transport ATP Transport Fatty Acid Transport Coenzyme A Transmembrane Transport FAD Transmembrane Transport NAD Transmembrane Transport AMP Transport
Pathways			Alpha-oxidation of phytanate Class I peroxisomal membrane protein import
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)	Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Coffee consumption ( 31046077) Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083) Feeling nervous ( 29500382) Irritable mood ( 29500382) Low density lipoprotein cholesterol levels ( 29083408) Neurociticism ( 29500382) Refractive error ( 32231278)
Interacting Genes		35 interacting genes: ABI3 AGR3 CCDC158 CDIP1 CDSN CENPM CTAG1A CTAG1B CTAG2 DAZAP2 ERP29 EVI2B FGF7 GOLM1 KLRF1 MEOX2 NME3 NT5C3A PRR5 RBX1 RNF4 RPS27A SHISA4 SHISA5 SLC25A17 SMIM21 TAS2R41 UBA52 UBB UBC UBQLN1 UBQLNL UHRF2 XPO1 ZBTB46	10 interacting genes: CACNA1S CD55 CIR1 DESI1 GRAP2 KCNJ13 MEOX2 PEX19 SEPTIN3 ZC3H7B
Entrez ID		27351	10478
HPRD ID		18590	08425
Ensembl ID		ENSG00000100418	ENSG00000100372
Uniprot IDs		Q6ICB0	B4DP73 B4DU97 F6RTR7 O43808
PDB IDs		3EBQ
Enriched GO Terms of Interacting Partners?
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