SESN1 and MIOS

Number of citations of the paper that reports this interaction (PubMedID 25263562)
166

Data Source:
BioGRID (affinity chromatography technology, pull down)

		SESN1	MIOS
Description		sestrin 1	meiosis regulator for oocyte development
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleoplasm Cytoplasm Lysosomal Membrane Cytosol Cell Junction GATOR2 Complex
	Molecular Function	Protein Binding Oxidoreductase Activity, Acting On Peroxide As Acceptor Peroxiredoxin Activity Leucine Binding	Protein Binding
	Biological Process	Positive Regulation Of Macroautophagy Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Cellular Response To Leucine Reactive Oxygen Species Metabolic Process Cellular Oxidant Detoxification Regulation Of Response To Reactive Oxygen Species Negative Regulation Of TORC1 Signaling Cellular Response To Leucine Starvation	Positive Regulation Of TOR Signaling Cellular Response To Amino Acid Starvation Cellular Protein-containing Complex Localization
Pathways		Amino acids regulate mTORC1	Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Asthma ( 32296059) Birth weight ( 31043758) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 27863252) Metabolite levels ( 23823483) Offspring birth weight ( 31043758) Prostate cancer ( 23535732)
Interacting Genes		3 interacting genes: MIOS PRDX1 WDR24	3 interacting genes: NTAQ1 SESN1 SESN3
Entrez ID		27244	54468
HPRD ID		07310	07898
Ensembl ID		ENSG00000080546	ENSG00000164654
Uniprot IDs		Q9Y6P5	A0A024RA24 Q9NXC5
PDB IDs
Enriched GO Terms of Interacting Partners?
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